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PLP1 抗体 (N-Term)

PLP1 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2778151
发货至: 中国
  • 抗原 See all PLP1 抗体
    PLP1 (Proteolipid Protein 1 (PLP1))
    抗原表位
    • 16
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 32
    • 24
    • 10
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼
    宿主
    • 36
    • 11
    • 3
    克隆类型
    • 40
    • 10
    多克隆
    标记
    • 26
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLP1 antibody is un-conjugated
    应用范围
    • 42
    • 19
    • 16
    • 13
    • 13
    • 11
    • 9
    • 7
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    GHEALTGTEK LIETYFSKNY QDYEYLINVI HAFQYVIYGT ASFFFLYGAL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%
    产品特性
    This is a rabbit polyclonal antibody against PLP1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PLP1
    Top Product
    Discover our top product PLP1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 277 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PLP1 (Proteolipid Protein 1 (PLP1))
    别名
    PLP1 (PLP1 产品)
    别名
    GPM6C antibody, HLD1 antibody, MMPL antibody, PLP antibody, PLP/DM20 antibody, PMD antibody, SPG2 antibody, Plp antibody, PLP1 antibody, plp1 antibody, DKFZp459O081 antibody, DKFZp459O113 antibody, DM20 antibody, jimpy antibody, jp antibody, msd antibody, rsh antibody, plp antibody, hld1 antibody, mmpl antibody, plp1a antibody, pmd antibody, spg2 antibody, DMalpha2c antibody, wu:fc27f01 antibody, wu:fj36d03 antibody, wu:fj42d08 antibody, zgc:110499 antibody, PLP-B antibody, plp1-a antibody, plp1-b antibody, plp1b antibody, proteolipid protein 1 antibody, proteolipid protein (myelin) 1 antibody, myelin proteolipid protein antibody, proteolipid protein 1 L homeolog antibody, proteolipid protein 1a antibody, proteolipid protein 1 S homeolog antibody, PLP1 antibody, Plp1 antibody, plp1 antibody, Tsp_11640 antibody, plp antibody, plp1.L antibody, plp1a antibody, plp1.S antibody
    背景
    PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.
    Alias Symbols: MMPL, PLP, PLP/DM20, PMD, SPG2, HLD1
    Protein Interaction Partner: PTPRN, CLN8, Htt, ITGAV, ITGA5, MAG, MBP, CANX, CALR,
    Protein Size: 277
    分子量
    30 kDa
    基因ID
    5354
    NCBI登录号
    NM_000533, NP_000524
    UniProt
    P60201
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