MED27 抗体 (Middle Region)
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- 抗原 See all MED27 抗体
- MED27 (Mediator Complex Subunit 27 (MED27))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, Cow, 犬, 大鼠, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MED27 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LSRPNGTSAM LLVTLGKVLK VIVVMRSLFI DRTIVKGYNE NVYTEDGKLD
- 预测反应
- Cow: 100%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MED27. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MED27
- Top Product
- Discover our top product MED27 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 311 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MED27 (Mediator Complex Subunit 27 (MED27))
- 别名
- MED27 (MED27 产品)
- 别名
- CRAP34 antibody, CRSP34 antibody, CRSP8 antibody, TRAP37 antibody, CG1245 antibody, Dmel\\CG1245 antibody, Med27 antibody, Trap37 antibody, dCRSP34 antibody, dCrsp34 antibody, dTRAP37 antibody, med27 antibody, crsp8 antibody, zgc:66302 antibody, MED27 antibody, DDBDRAFT_0216764 antibody, DDBDRAFT_0266847 antibody, DDB_0216764 antibody, DDB_0266847 antibody, 1500015J03Rik antibody, 2310042P07Rik antibody, AA682045 antibody, Crsp8 antibody, D2Ertd434e antibody, RGD1564993 antibody, DKFZp459I1912 antibody, CRSP complex subunit 8-B antibody, Xcrsp34 antibody, crap34 antibody, crsp34 antibody, crsp8-B antibody, med27-a antibody, med27-b antibody, trap37 antibody, mediator complex subunit 27 antibody, Mediator complex subunit 27 antibody, cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa antibody, hypothetical protein antibody, mediator complex subunit 27 S homeolog antibody, MED27 antibody, med27 antibody, crsp8 antibody, Med27 antibody, med27.S antibody
- 背景
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. MED27 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Alias Symbols: CRAP34, CRSP34, CRSP8, MGC11274, TRAP37
Protein Interaction Partner: UBC, CDK19, CDK8, MED19, ARFGAP1, MED26, SOX5, POLR2C, RBPJ, AFP, FBXW7, EPAS1, MED4, MED12, MED14, MED1, MED28, OBFC1, MED18, ZC3H13, QKI, TRIP4, TADA2A, MED9, MED30, MED8, MED22, MED10, MED29,
Protein Size: 311 - 分子量
- 35 kDa
- 基因ID
- 9442
- NCBI登录号
- NM_004269, NP_004260
- UniProt
- Q6P2C8
- 途径
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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