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Claudin 5 抗体 (C-Term)

CLDN5 适用: 人, 大鼠, 小鼠, Pig, Cow, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN487102
发货至: 中国
  • 抗原 See all Claudin 5 (CLDN5) 抗体
    Claudin 5 (CLDN5)
    抗原表位
    • 10
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 60
    • 37
    • 35
    • 18
    • 17
    • 14
    • 3
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, Pig, Cow, 兔, 豚鼠
    宿主
    • 56
    • 6
    克隆类型
    • 48
    • 14
    多克隆
    标记
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Claudin 5 antibody is un-conjugated
    应用范围
    • 34
    • 20
    • 19
    • 12
    • 7
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    GWAATALLMV GGCLLCCGAW VCTGRPDLSF PVKYSAPRRP TATGDYDKKN
    预测反应
    Cow: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against CLDN5. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN5
    亚型
    IgG
    Top Product
    Discover our top product CLDN5 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 218 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yang, Liu, Miao, Yang, Fu, Dou, Cai, Zong, Tan, Chen, Wang: "Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier." in: Oncotarget, Vol. 7, Issue 39, pp. 63839-63855, (2016) (PubMed).

    Fontijn, Volger, Fledderus, Reijerkerk, de Vries, Horrevoets: "SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function." in: American journal of physiology. Heart and circulatory physiology, Vol. 294, Issue 2, pp. H891-900, (2008) (PubMed).

  • 抗原
    Claudin 5 (CLDN5)
    别名
    CLDN5 (CLDN5 产品)
    背景
    CLDN5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: AWAL, BEC1, CPETRL1, TMVCF
    Protein Interaction Partner: UBC, MPDZ, CLDN3, CLDN5, TJP1, CLDN1,
    Protein Size: 218
    分子量
    23 kDa
    基因ID
    7122
    NCBI登录号
    NM_003277, NP_003268
    UniProt
    O00501
    途径
    Hepatitis C
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