Claudin 5 抗体 (C-Term)
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- 抗原 See all Claudin 5 (CLDN5) 抗体
- Claudin 5 (CLDN5)
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠, Pig, Cow, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Claudin 5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GWAATALLMV GGCLLCCGAW VCTGRPDLSF PVKYSAPRRP TATGDYDKKN
- 预测反应
- Cow: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against CLDN5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN5
- 亚型
- IgG
- Top Product
- Discover our top product CLDN5 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 218 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier." in: Oncotarget, Vol. 7, Issue 39, pp. 63839-63855, (2016) (PubMed).
: "SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function." in: American journal of physiology. Heart and circulatory physiology, Vol. 294, Issue 2, pp. H891-900, (2008) (PubMed).
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Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier." in: Oncotarget, Vol. 7, Issue 39, pp. 63839-63855, (2016) (PubMed).
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- 抗原
- Claudin 5 (CLDN5)
- 别名
- CLDN5 (CLDN5 产品)
- 别名
- AWAL antibody, BEC1 antibody, CPETRL1 antibody, TMVCF antibody, cld5 antibody, awal antibody, bec1 antibody, claudin-5 antibody, cpetrl1 antibody, tmvcf antibody, AI854493 antibody, MBEC1 antibody, Tmvcf antibody, cldn5 antibody, zgc:85723 antibody, zgc:103419 antibody, claudin 5 antibody, Claudin-5 antibody, claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) antibody, claudin 5a antibody, claudin 5b antibody, claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) L homeolog antibody, CLDN5 antibody, cld5 antibody, cldn5 antibody, Cldn5 antibody, cldn5a antibody, cldn5b antibody, cldn5.L antibody
- 背景
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CLDN5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AWAL, BEC1, CPETRL1, TMVCF
Protein Interaction Partner: UBC, MPDZ, CLDN3, CLDN5, TJP1, CLDN1,
Protein Size: 218 - 分子量
- 23 kDa
- 基因ID
- 7122
- NCBI登录号
- NM_003277, NP_003268
- UniProt
- O00501
- 途径
- Hepatitis C
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