STAT4 抗体 (N-Term)
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- 抗原 See all STAT4 抗体
- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Pig, 犬, 兔, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STAT4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- IGGPLHNGLD QLQNCFTLLA ESLFQLRRQL EKLEEQSTKM TYEGDPIPMQ
- 预测反应
- Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%
- 产品特性
- This is a rabbit polyclonal antibody against STAT4. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human STAT4
- Top Product
- Discover our top product STAT4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 748 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26789-96, (2004) (PubMed).
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Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26789-96, (2004) (PubMed).
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- 抗原
- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
- 别名
- STAT4 (STAT4 产品)
- 别名
- SLEB11 antibody, signal transducer and activator of transcription 4 antibody, STAT4 antibody, stat4 antibody, Stat4 antibody
- 背景
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STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.
Alias Symbols: SLEB11
Protein Interaction Partner: UBC, ADRB2, TRIM28, FHL1, ZNF467, PIAS2, NMI, IL12RB2, IL12RB1, MAP2K6, STAT4, MAPK14, CREBBP, JUN, STAT3, IFNGR1,
Protein Size: 748 - 分子量
- 86 kDa
- 基因ID
- 6775
- NCBI登录号
- NM_003151, NP_003142
- UniProt
- Q14765
- 途径
- JAK/STAT Signaling
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