Sp3 抗体 (Middle Region)
-
- 抗原 See all Sp3 抗体
- Sp3 (Sp3 Transcription Factor (Sp3))
-
抗原表位
- Middle Region
-
适用
- 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Sp3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- TAGINADGHL INTGQAMDSS DNSERTGERV SPDINETNTD TDLFVPTSSS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SP3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SP3
- Top Product
- Discover our top product Sp3 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 781 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- Sp3 (Sp3 Transcription Factor (Sp3))
- 别名
- SP3 (Sp3 产品)
- 别名
- SPR2 antibody, D130027J01Rik antibody, SP3 antibody, sp3 antibody, zgc:162922 antibody, Sp3 transcription factor antibody, trans-acting transcription factor 3 antibody, sp3a transcription factor antibody, Sp3 transcription factor S homeolog antibody, SP3 antibody, Sp3 antibody, sp3a antibody, sp3.S antibody
- 背景
-
SP3 is a transcriptional factor that can act as an activator or repressor, probably in a isoform-specific manner. SP3 binds to GT and GC boxes promoters elements.This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted.
Alias Symbols: DKFZp686O1631, SPR-2, SPR2
Protein Interaction Partner: SP1, SUMO1, PPP2R4, PPP1CC, GCH1, HLTF, TFAP4, YY1, SUMO2, UBC, RELA, MECP2, HDAC2, HDAC1, ZBTB7B, EP300, CRX, TP53, NKX3-1, CREBBP, CEBPB, ESR1, DNMT1, SFPQ, PIAS1, GRIN1, GABPA, ZBTB7A, UBE2I, STK19, RBBP4, E2F1, RB1, SP4, TNFSF10, SENP1,
Protein Size: 781 - 分子量
- 82 kDa
- 基因ID
- 6670
- NCBI登录号
- NM_003111, NP_003102
- UniProt
- Q02447
-