SOX5 抗体 (C-Term)
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- 抗原 See all SOX5 抗体
- SOX5 (SRY (Sex Determining Region Y)-Box 5 (SOX5))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠, 兔, 豚鼠, 马, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOX5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PEPGMPVIQS TYGVKGEEPH IKEEIQAEDI NGEIYDEYDE EEDDPDVDYG
- 特异性
- Designed to recognize all five isoforms of human SOX5 (84, 82, 42, 71 and 83 kDa)
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SOX5. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human SOX5
- Top Product
- Discover our top product SOX5 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 377 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5." in: BMC molecular biology, Vol. 18, Issue 1, pp. 2, (2017) (PubMed).
: "Alteration of rat fetal cerebral cortex development after prenatal exposure to polychlorinated biphenyls." in: PLoS ONE, Vol. 9, Issue 3, pp. e91903, (2014) (PubMed).
: "Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage." in: PLoS ONE, Vol. 8, Issue 5, pp. e62994, (2013) (PubMed).
: "Sonic Hedgehog-signalling patterns the developing chicken comb as revealed by exploration of the pea-comb mutation." in: PLoS ONE, Vol. 7, Issue 12, pp. e50890, (2012) (PubMed).
: "Array-based comparative genomic hybridization identifies CDK4 and FOXM1 alterations as independent predictors of survival in malignant peripheral nerve sheath tumor." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 7, pp. 1924-34, (2011) (PubMed).
: "SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer." in: Human molecular genetics, Vol. 20, Issue 8, pp. 1547-59, (2011) (PubMed).
: "Transcriptional regulation of an axonemal central apparatus gene, sperm-associated antigen 6, by a SRY-related high mobility group transcription factor, S-SOX5." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30496-505, (2010) (PubMed).
: "Neoplasms with schwannian differentiation express transcription factors known to regulate normal schwann cell development." in: International journal of surgical pathology, Vol. 18, Issue 6, pp. 449-57, (2010) (PubMed).
: "Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling." in: Nature, Vol. 461, Issue 7263, pp. 524-8, (2009) (PubMed).
: "Copy number variation in intron 1 of SOX5 causes the Pea-comb phenotype in chickens." in: PLoS genetics, Vol. 5, Issue 6, pp. e1000512, (2009) (PubMed).
: "Sox5 can suppress platelet-derived growth factor B-induced glioma development in Ink4a-deficient mice through induction of acute cellular senescence." in: Oncogene, Vol. 28, Issue 12, pp. 1537-48, (2009) (PubMed).
: "Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes." in: BMC genomics, Vol. 9, pp. 254, (2008) (PubMed).
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Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5." in: BMC molecular biology, Vol. 18, Issue 1, pp. 2, (2017) (PubMed).
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- 抗原
- SOX5 (SRY (Sex Determining Region Y)-Box 5 (SOX5))
- 别名
- SOX5 (SOX5 产品)
- 别名
- L-SOX5 antibody, XSox-5 antibody, l-sox5 antibody, A730017D01Rik antibody, AI528773 antibody, Sox5l1 antibody, xSox5 antibody, id:ibd5067 antibody, sb:eu456 antibody, si:dkey-215a8.1 antibody, SRY-box 5 antibody, SRY (sex determining region Y)-box 5 antibody, SRY box 5 antibody, SRY-box 5 S homeolog antibody, SOX5 antibody, sox5 antibody, Sox5 antibody, sox5.S antibody
- 背景
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SOX5 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8.
Alias Symbols: L-SOX5, MGC35153
Protein Interaction Partner: SUMO1P1, MORN3, PRR20A, FAM46B, CBX8, ZNF581, ARID5A, KAT5, CDC23, TAF6, SOX5, LMO2, LMO1, KIFC3, CRX, AES, MED27, UQCRFS1, TTC1, RPS2, SMAD7, SMAD5, SMAD1, FTH1, CDK6, CDC25A, APP, SOX2, SOX6,
Protein Size: 377 - 分子量
- 42 kDa
- 基因ID
- 6660
- NCBI登录号
- NM_178010, NP_821078
- UniProt
- P35711
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