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MRPS15 抗体 (N-Term)

MRPS15 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777848
发货至: 中国
  • 抗原 See all MRPS15 抗体
    MRPS15 (Mitochondrial Ribosomal Protein S15 (MRPS15))
    抗原表位
    • 7
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马, 犬
    宿主
    • 31
    • 2
    克隆类型
    • 31
    • 2
    多克隆
    标记
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MRPS15 antibody is un-conjugated
    应用范围
    • 25
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    RGYVVRKPAQ SRLDDDPPPS TLLKDYQNVP GIEKVDDVVK RLLSLEMANK
    预测反应
    Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 83%, Rabbit: 86%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against MRPS15. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human MRPS15
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 257 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Davies, Rackham, Shearwood, Hamilton, Narsai, Whelan, Filipovska: "Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation." in: FEBS letters, Vol. 583, Issue 12, pp. 1853-8, (2009) (PubMed).

  • 抗原
    MRPS15 (Mitochondrial Ribosomal Protein S15 (MRPS15))
    别名
    MRPS15 (MRPS15 产品)
    别名
    CG4207 antibody, DmMRPS15 antibody, Dmel\\CG4207 antibody, MRP-S15 antibody, mRpS15 antibody, zgc:92862 antibody, MPR-S15 antibody, RPMS15 antibody, S15mt antibody, 1500003E24Rik antibody, 2410002B11Rik antibody, Mprs15 antibody, CG4207 gene product from transcript CG4207-RA antibody, mitochondrial ribosomal protein S15 antibody, mitochondrial ribosomal protein S15 L homeolog antibody, bonsai antibody, mrps15 antibody, MRPS15 antibody, mrpS15 antibody, mrps15.L antibody, Mrps15 antibody
    背景
    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPS15 is a 28S subunit protein that belongs to the ribosomal protein S15P family.Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q.
    Alias Symbols: DC37, FLJ11564, MPR-S15, RPMS15, S15mt
    Protein Interaction Partner: GRSF1, UBC, PARK2, ESR2, PTCD3, CAND1, COPS5, CUL3, SUMO2, ICT1,
    Protein Size: 257
    分子量
    30 kDa
    基因ID
    64960
    NCBI登录号
    NM_031280, NP_112570
    UniProt
    P82914
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