BCL11B 抗体 (Middle Region)
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- 抗原 See all BCL11B 抗体
- BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, Cow, 犬, 大鼠, 豚鼠, 兔, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BCL11B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- QASKLKRHMK THMHKAGSLA GRSDDGLSAA SSPEPGTSEL AGEGLKAADG
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against BCL11B. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human BCL11B
- Top Product
- Discover our top product BCL11B Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 823 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
- 别名
- BCL11B (BCL11B 产品)
- 别名
- BCL11B antibody, 9130430L19Rik antibody, AI604821 antibody, B630002E05Rik antibody, BCL-11B antibody, Ctip2 antibody, Rit1 antibody, ATL1 antibody, ATL1-alpha antibody, ATL1-beta antibody, ATL1-delta antibody, ATL1-gamma antibody, CTIP-2 antibody, CTIP2 antibody, RIT1 antibody, ZNF856B antibody, hRIT1-alpha antibody, B-cell CLL/lymphoma 11B antibody, B cell leukemia/lymphoma 11B antibody, B-cell CLL/lymphoma 11B (zinc finger protein) antibody, BCL11B antibody, Bcl11b antibody
- 背景
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BCL11B is the tumor-suppressor protein involved in T-cell lymphomas. BCL11B may function on the P53-signaling pathway. BCL11B may be a key regulator of both differentiation and survival during thymocyte development. BCL11B repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.
Alias Symbols: CTIP-2, CTIP2, RIT1, hRIT1-alpha, ZNF856B
Protein Interaction Partner: HDAC6, HDAC2, HDAC1, NOTCH1, UBC, HDAC3, SUV39H1, tat, CBX5, NR2F1, SP1, MBD3, MTA2, MTA1, RBBP7, RBBP4, CHD4, NR2F2,
Protein Size: 823 - 分子量
- 88 kDa
- 基因ID
- 64919
- NCBI登录号
- NM_022898, NP_075049
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