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PRDM16 抗体 (Middle Region)

PRDM16 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 犬, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777828
发货至: 中国
  • 抗原 See all PRDM16 抗体
    PRDM16 (PR Domain Containing 16 (PRDM16))
    抗原表位
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    人, 小鼠, 大鼠, 豚鼠, 马, 犬, Cow, Pig
    宿主
    • 14
    • 2
    • 1
    • 1
    克隆类型
    • 16
    • 2
    多克隆
    标记
    • 14
    • 2
    • 1
    • 1
    This PRDM16 antibody is un-conjugated
    应用范围
    • 12
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    LNHTQDAKLP SPLGNPALPL VSAVSNSSQG TTAAAGPEEK FESRLEDSCV
    预测反应
    Cow: 92%, Dog: 77%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 79%, Pig: 92%, Rat: 86%
    产品特性
    This is a rabbit polyclonal antibody against PRDM16. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human PRDM16
    Top Product
    Discover our top product PRDM16 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 1275 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PRDM16 (PR Domain Containing 16 (PRDM16))
    别名
    PRDM16 (PRDM16 产品)
    别名
    PRDM16 antibody, wu:fc09g08 antibody, MEL1 antibody, PFM13 antibody, 5730557K01Rik antibody, C130091E20 antibody, csp1 antibody, mKIAA1675 antibody, mel1 antibody, PR/SET domain 16 antibody, PR domain containing 16 antibody, PRDM16 antibody, prdm16 antibody, Prdm16 antibody
    背景
    The reciprocal translocation t(1,3)(p36,q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: KIAA1675, MEL1, PFM13
    Protein Interaction Partner: TFAP4, UBC, HDAC2, Ctbp2, SUMO1, SKI, SMAD3, SMAD2, INADL,
    Protein Size: 1275
    分子量
    140 kDa
    基因ID
    63976
    NCBI登录号
    NM_022114, NP_071397
    UniProt
    Q9HAZ2
    途径
    Stem Cell Maintenance, Brown Fat Cell Differentiation
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