PRDM12 抗体 (N-Term)
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- 抗原 See all PRDM12 抗体
- PRDM12 (PR Domain Containing 12 (PRDM12))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, Pig, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRDM12 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- SFLYGRWRNV LGEQLFEDKS HHASPKTAFT AEVLAQSFSG EVQKLSSLVL
- 预测反应
- Cow: 100%, Dog: 91%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%, Zebrafish: 83%
- 产品特性
- This is a rabbit polyclonal antibody against PRDM12. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRDM12
- Top Product
- Discover our top product PRDM12 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 367 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PRDM12 (PR Domain Containing 12 (PRDM12))
- 别名
- PRDM12 (PRDM12 产品)
- 别名
- PRDM12 antibody, prdm12 antibody, MGC146714 antibody, PFM9 antibody, pfm9 antibody, Gm998 antibody, PR/SET domain 12 antibody, PR domain containing 12 antibody, PR domain containing 12 L homeolog antibody, PR domain containing 12a antibody, PRDM12 antibody, prdm12 antibody, prdm12.L antibody, Prdm12 antibody, prdm12a antibody
- 背景
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PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
Alias Symbols: PFM9
Protein Size: 367 - 分子量
- 40 kDa
- 基因ID
- 59335
- NCBI登录号
- NM_021619, NP_067632
- UniProt
- Q9H4Q4
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