Retinoblastoma 1 抗体 (C-Term)
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- 抗原 See all Retinoblastoma 1 (RB1) 抗体
- Retinoblastoma 1 (RB1)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Retinoblastoma 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- IMMCSMYGIC KVKNIDLKFK IIVTAYKDLP HAVQETFKRV LIKEEEYDSI
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against RB1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RB1
- Top Product
- Discover our top product RB1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 928 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Retinoblastoma 1 (RB1)
- 别名
- RB1 (RB1 产品)
- 背景
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Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.
Alias Symbols: RB, pRb, OSRC, pp110, p105-Rb
Protein Interaction Partner: RAF1, E2F1, ABL1, HDAC1, KDM2A, SMARCA4, USP7, UBC, DYRK1A, NEFM, DYRK1B, MAGEA11, ENC1, PPP1CA, CDKN1C, CDKN1A, CDK6, CDK4, CDK2, CCNE1, CCNA2, CCND1, HDAC11, PAX5, HIF1A, E2F4, CEBPE, CCNA1, SUMO1, UBE2I, TFAP2A, CDK3, CDK1, CCNC, CCNB1, MRPS18B, SUMO2,
Protein Size: 928 - 分子量
- 106 kDa
- 基因ID
- 5925
- NCBI登录号
- NM_000321, NP_000312
- UniProt
- P06400
- 途径
- Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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