PURA 抗体 (Middle Region)
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- 抗原 See all PURA 抗体
- PURA (Purine-Rich Element Binding Protein A (PURA))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 兔, 绵羊, Cow, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PURA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- VEFRDYLGDF IEHYAQLGPS QPPDLAQAQD EPRRALKSEF LVRENRKYYM
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PURA. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PURA
- Top Product
- Discover our top product PURA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 322 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PURA (Purine-Rich Element Binding Protein A (PURA))
- 别名
- PURA (PURA 产品)
- 别名
- CAGER-1 antibody, Pur-alpha antibody, ssCRE-BP antibody, PUR-ALPHA antibody, PUR1 antibody, PURALPHA antibody, zgc:103411 antibody, pur-alpha antibody, pur1 antibody, puralpha antibody, purine-rich element binding protein A antibody, purine rich element binding protein A antibody, purine-rich element binding protein Aa antibody, purine-rich element binding protein A L homeolog antibody, pura antibody, Pura antibody, PURA antibody, puraa antibody, pura.L antibody
- 背景
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PURA is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PUR-ALPHA, PUR1, PURALPHA
Protein Interaction Partner: RAF1, UBC, LIN28B, LIN28A, BMI1, TARDBP, IGSF8, ICAM1, IL7R, ZNF638, DDX23, RFC3, RFC2, RB1, PURB, POLA1, CAND1, CUL1, CUL3, EIF2AK2, POU5F1, MEPCE, HNRNPA1, ADAP1, CCNT1, E2F1, SP1, YBX1, CDK5, CNBP, Jvgp5,
Protein Size: 322 - 分子量
- 35 kDa
- 基因ID
- 5813
- NCBI登录号
- NM_005859, NP_005850
- UniProt
- Q00577
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