PPARA 抗体 (N-Term)
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- 抗原 See all PPARA 抗体
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, Cow, 山羊, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPARA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EISQSIGEDS SGSFGFTEYQ YLGSCPGSDG SVITDTLSPA SSPSSVTYPV
- 预测反应
- Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PPARA. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the n terminal region of human PPARA
- Top Product
- Discover our top product PPARA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 468 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
- 别名
- PPARA (PPARA 产品)
- 别名
- NR1C1 antibody, PPAR antibody, PPARalpha antibody, hPPAR antibody, LOC100136415 antibody, PPARALPHA antibody, nr1c1 antibody, xPPARalpha antibody, xppara antibody, 4933429D07Rik antibody, AW742785 antibody, Nr1c1 antibody, PPAR-alpha antibody, Ppar antibody, peroxisome proliferator activated receptor alpha antibody, peroxisome proliferator-activated receptor alpha antibody, peroxisome proliferator activated receptor alpha L homeolog antibody, PPARA antibody, LOC100136415 antibody, ppara.L antibody, Ppara antibody, ppara antibody
- 背景
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Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. PPARA is the subtype PPAR-alpha, which is a nuclear transcription factor.Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
Alias Symbols: MGC2237, MGC2452, NR1C1, PPAR, hPPAR, PPARalpha
Protein Interaction Partner: SIRT1, PRMT1, PRMT8, RXRA, CHD9, NCOA1, FOXA3, CDK3, TNP1, HSP90AA1, NCOR2, NCOR1, SUMO1, UBE2I, LPIN1, SRC, TRA, MECR, STAC3, HELZ2, NRBF2, AIP, NR1H3, MED24, GADD45G, GADD45B, AKAP13, PPARGC1A, MED1, EP300, NRIP1, DAP3, MAPK3, DUT, RXRG, PRKCD, PRKCA, M
Protein Size: 468 - 分子量
- 52 kDa
- 基因ID
- 5465
- NCBI登录号
- NM_005036, NP_005027
- UniProt
- Q07869
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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