SOX18 抗体 (Middle Region)
(3 references)-
- 抗原 See all SOX18 抗体
- SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOX18 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- RTAPPAAPLA GLYYGTLGTP GPYPGPLSPP PEAPPLESAE PLGPAADLWA
- 预测反应
- Cow: 86%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SOX18. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SOX18
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anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 63-150) antibody
SOX18 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 153-377) antibodySOX18 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 271-320) antibodySOX18 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, Pig, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 63-150) antibodySOX18 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 192-241) antibodySOX18 适用: 人, 小鼠, 大鼠, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) (AA 1-100) antibodySOX18 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) antibodySOX18 适用: 人 WB, IF/ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 384 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity." in: The Journal of clinical investigation, Vol. 124, Issue 9, pp. 3960-74, (2014) (PubMed).
: "Endothelial ERK signaling controls lymphatic fate specification." in: The Journal of clinical investigation, Vol. 123, Issue 3, pp. 1202-15, (2013) (PubMed).
: "Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice." in: Cancer research, Vol. 72, Issue 12, pp. 3105-14, (2012) (PubMed).
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: "Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity." in: The Journal of clinical investigation, Vol. 124, Issue 9, pp. 3960-74, (2014) (PubMed).
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- 抗原
- SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))
- 别名
- SOX18 (SOX18 产品)
- 别名
- HLTS antibody, AI385749 antibody, Ra antibody, Ragl antibody, sox18 antibody, xSox18alpha antibody, xSox18beta antibody, xsox18 antibody, SRY-box 18 antibody, SRY (sex determining region Y)-box 18 antibody, SRY box 18 antibody, SRY-box 18 S homeolog antibody, SRY-box 18 L homeolog antibody, SRY box 1 antibody, SOX18 antibody, Sox18 antibody, sox18.S antibody, sox18.L antibody, Sox1 antibody
- 背景
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SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
Alias Symbols: HLTS
Protein Interaction Partner: GKAP1, MECP2, MEF2C, HMGB1,
Protein Size: 384 - 分子量
- 41 kDa
- 基因ID
- 54345
- NCBI登录号
- NM_018419, NP_060889
- UniProt
- P35713
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