Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial (N-Term) 抗体
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- 抗原
- Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB)
- 序列
- AAGFGRCCRV LRSISRFHWR SQHTKANRQR EPGLGFSFEF TEQQKEFQAT
- 预测反应
- Cow: 92%, Horse: 92%, Human: 100%, Mouse: 91%, Rat: 91%
- 产品特性
- This is a rabbit polyclonal antibody against ACADM. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACADM
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 421 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial
- 别名
- ACADM
- 背景
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ACADM Is the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Clinical phenotypes are associated with ACADM hereditary deficiency.This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ACAD1, MCAD, MCADH
Protein Interaction Partner: SUMO2, SUMO3, UBC, MDM2, STRAP, HDAC1, UBD, CUL3, SUMO4, CALM1, USP50, USP20, ACADM,
Protein Size: 421 - 分子量
- 46 kDa
- 基因ID
- 34
- NCBI登录号
- NM_000016, NP_000007
- UniProt
- P11310
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