HIC1 抗体 (N-Term)
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- 抗原 See all HIC1 抗体
- HIC1 (Hypermethylated in Cancer 1 (HIC1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 豚鼠, 犬, Cow, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HIC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RRCSPLCGLD LSKKSPPGSA APERPLAERE LPPRPDSPPS AGPAAYKEPP
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 85%
- 产品特性
- This is a rabbit polyclonal antibody against HIC1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HIC1
- Top Product
- Discover our top product HIC1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 714 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma." in: Oncogene, Vol. 27, Issue 18, pp. 2613-25, (2008) (PubMed).
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Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma." in: Oncogene, Vol. 27, Issue 18, pp. 2613-25, (2008) (PubMed).
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- 抗原
- HIC1 (Hypermethylated in Cancer 1 (HIC1))
- 别名
- HIC1 (HIC1 产品)
- 别名
- zfHIC1 antibody, HIC1 antibody, ZBTB29 antibody, ZNF901 antibody, hic-1 antibody, AA408311 antibody, HIC-1 antibody, hypermethylated in cancer 1 antibody, HIC ZBTB transcriptional repressor 1 antibody, hic1 antibody, HIC1 antibody, Hic1 antibody
- 背景
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HIC1 is a transcriptional repressor. HIC1 may act as a tumor suppressor. HIC1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIC1 may be a cause of the facial dysmorphism and additional birth defects (except for liss
Alias Symbols: ZBTB29, hic-1, ZNF901
Protein Interaction Partner: PIAS4, PIAS3, PIAS2, SP1, STAT3, SIRT1, MTA1, UBE2I, SUMO2, HIC2, TCF4, CTBP2, CTBP1, EED, PHF1, EZH2, PHF19, SUZ12, UBC, MBD3, RBBP4, CHD3, SENP3, HDAC4, PIAS1, ARID1A, HIC1, HDAC1,
Protein Size: 714 - 分子量
- 74 kDa
- 基因ID
- 3090
- NCBI登录号
- NM_006497, NP_006488
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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