HCLS1 抗体 (N-Term)
(1 reference)-
- 抗原 See all HCLS1 抗体
- HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HCLS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- VNDISEKEQR WGAKTIEGSG RTEHINIHQL RNKVSEEHDV LRKKEMESGP
- 预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against HCLS1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HCLS1
- Top Product
- Discover our top product HCLS1 Primary Antibody
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anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) (AA 266-355) antibody
HCLS1 适用: 人 WB, ELISA, IHC (p), PLA, RNAi 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) (AA 266-355) antibodyHCLS1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2A9 unconjugated
anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) (AA 161-260) antibodyHCLS1 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) (AA 1-280) antibodyHCLS1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) (C-Term) antibodyHCLS1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) (AA 28-77) antibodyHCLS1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) (AA 362-391), (C-Term) antibodyHCLS1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB34076 unconjugated
anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) (C-Term) antibodyHCLS1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) (pTyr397) antibodyHCLS1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) antibodyHCLS1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 486 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells." in: The Biochemical journal, Vol. 364, Issue Pt 1, pp. 41-7, (2002) (PubMed).
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: "Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells." in: The Biochemical journal, Vol. 364, Issue Pt 1, pp. 41-7, (2002) (PubMed).
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- 抗原
- HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))
- 别名
- HCLS1 (HCLS1 产品)
- 别名
- CTTNL antibody, HS1 antibody, AW213261 antibody, HCLS1 antibody, hcls1 antibody, si:dkey-9a20.6 antibody, wu:fk96b08 antibody, zgc:154014 antibody, hematopoietic cell-specific Lyn substrate 1 antibody, hematopoietic cell specific Lyn substrate 1 antibody, hematopoietic lineage cell-specific protein-like antibody, HCLS1 antibody, Hcls1 antibody, LOC100223649 antibody, hcls1 antibody
- 背景
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HCLS1 Tyr phosphorylation catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets. This gene is a substrate for caspase cleavage during apoptosis.
Alias Symbols: HS1, CTTNL
Protein Interaction Partner: SH2D4A, UBC, Mbp, Dlg4, NOTCH1, QKI, TERF1, TRIM29, SSBP3, BLZF1, IKBKG, LZTR1, ZBTB25, HS1BP3, HAX1, ACTR2, MAP4K1, CASP3, SYK, WAS, LYN, FGR, CSNK2A1, CD79A, ACTA1, GRB2, ACTR3,
Protein Size: 486 - 分子量
- 54 kDa
- 基因ID
- 3059
- NCBI登录号
- NM_005335, NP_005326
- UniProt
- P14317
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Maintenance of Protein Location
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