GATA2 抗体 (N-Term)
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- 抗原 See all GATA2 抗体
- GATA2 (GATA Binding Protein 2 (GATA2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GATA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- PYYANPAHAR ARVSYSPAHA RLTGGQMCRP HLLHSPGLPW LDGGKAALSA
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against GATA2. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GATA2
- Top Product
- Discover our top product GATA2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 480 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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A regulatory circuit comprising GATA1/2 switch and microRNA-27a/24 promotes erythropoiesis." in: Nucleic acids research, Vol. 42, Issue 1, pp. 442-57, (2013) (PubMed).
: "Gene expression profiling identifies HOXB4 as a direct downstream target of GATA-2 in human CD34+ hematopoietic cells." in: PLoS ONE, Vol. 7, Issue 9, pp. e40959, (2012) (PubMed).
: "GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis." in: The Journal of biological chemistry, Vol. 285, Issue 42, pp. 32405-14, (2010) (PubMed).
: "The functional IGFBP7 promoter -418G>A polymorphism and risk of head and neck cancer." in: Mutation research, Vol. 702, Issue 1, pp. 32-9, (2010) (PubMed).
: "A mechanosensitive transcriptional mechanism that controls angiogenesis." in: Nature, Vol. 457, Issue 7233, pp. 1103-8, (2009) (PubMed).
: "Cross talk between retinoic acid signaling and transcription factor GATA-2." in: Molecular and cellular biology, Vol. 24, Issue 15, pp. 6824-36, (2004) (PubMed).
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A regulatory circuit comprising GATA1/2 switch and microRNA-27a/24 promotes erythropoiesis." in: Nucleic acids research, Vol. 42, Issue 1, pp. 442-57, (2013) (PubMed).
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- 抗原
- GATA2 (GATA Binding Protein 2 (GATA2))
- 别名
- GATA2 (GATA2 产品)
- 背景
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The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells is essential for normal primitive and definitive erythropoiesis and is expressed at high levels in erythroid cells, mast cells, and megakaryocytes. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.
Alias Symbols: DCML, NFE1B, MONOMAC
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-9, KRT40, PRR20A, ADAMTSL4, TRAF1, PSMA3, MDFI, GOLGA2, FHL3, TRIM23, AKT1, BMI1, SPI1, SMAD4, ELAVL1, KAT2A, EP300, MED1, POU1F1, POU2AF1, ZBTB32, ZFPM1, ZBTB16, HDAC5, HDAC3, HHEX, RARA, RXRA, MAPK1, JUN, CEBPA, STAT3, PML,
Protein Size: 480 - 分子量
- 50 kDa
- 基因ID
- 2624
- NCBI登录号
- NM_032638, NP_116027
- UniProt
- P23769
- 途径
- Stem Cell Maintenance
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