SOX2 抗体 (N-Term)
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- 抗原 See all SOX2 抗体
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 山羊, Pig, Cow, 绵羊, 斑马鱼, 马, 兔, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOX2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 91%
- 产品特性
- This is a rabbit polyclonal antibody against SOX2. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SOX2
- Top Product
- Discover our top product SOX2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 317 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Unique expression patterns of the embryonal stem cell marker SOX2 and hormone receptors suggest the existence of a subpopulation of epithelial stem/progenitor cells in porcine and bovine endometrium." in: Veterinary medicine and science, (2022) (PubMed).
: "Expression of pluripotency factors in larval epithelia of the frog Xenopus: evidence for the presence of cornea epithelial stem cells." in: Developmental biology, Vol. 374, Issue 2, pp. 281-94, (2013) (PubMed).
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Unique expression patterns of the embryonal stem cell marker SOX2 and hormone receptors suggest the existence of a subpopulation of epithelial stem/progenitor cells in porcine and bovine endometrium." in: Veterinary medicine and science, (2022) (PubMed).
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- 抗原
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- 别名
- SOX2 (SOX2 产品)
- 别名
- ANOP3 antibody, MCOPS3 antibody, RGD1565646 antibody, Sox-2 antibody, lcc antibody, ysb antibody, cb236 antibody, wu:fb83g04 antibody, wu:fc14d07 antibody, zgc:65860 antibody, zgc:77389 antibody, SRY-box2 antibody, Xsox-2 antibody, anop3 antibody, mcops3 antibody, sox-2 antibody, SRY-box 2 antibody, SRY box 2 antibody, SRY (sex determining region Y)-box 2 antibody, SRY-box 2 S homeolog antibody, SOX2 antibody, Sox2 antibody, sox2 antibody, sox2.S antibody
- 背景
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SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ANOP3, MCOPS3, MGC2413
Protein Interaction Partner: SUMO1, DMAP1, TBX2, SETD7, FAM21A, FZR1, MMS19, MRPS35, ZNF462, LSM2, CCAR2, MIER1, ZDBF2, CHD8, EP400, TSHZ3, RANBP10, ZNF687, XPO5, INTS2, MTA3, CORO1B, CASC5, MRPS22, KCMF1, MEPCE, TRERF1, INTS9, PARVA, SCYL2, CHD7, ZCCHC8, SOX6, BRIX1, SAMD4B, GID8, C
Protein Size: 317 - 分子量
- 34 kDa
- 基因ID
- 6657
- NCBI登录号
- NM_003106, NP_003097
- UniProt
- P48431
- 途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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