PHOX2A 抗体 (N-Term)
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- 抗原 See all PHOX2A 抗体
- PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PHOX2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- AVPYKFFPEP SGLHEKRKQR RIRTTFTSAQ LKELERVFAE THYPDIYTRE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against PHOX2A. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PHOX2A
- Top Product
- Discover our top product PHOX2A Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 284 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
- 别名
- PHOX2A (PHOX2A 产品)
- 别名
- ARIX antibody, CFEOM2 antibody, FEOM2 antibody, NCAM2 antibody, PMX2A antibody, Arix antibody, Phox2 antibody, Pmx2 antibody, Pmx2a antibody, arix antibody, sou antibody, zgc:77364 antibody, phox2 antibody, xphox2a antibody, paired like homeobox 2a antibody, paired-like homeobox 2a antibody, paired like homeobox 2a S homeolog antibody, PHOX2A antibody, Phox2a antibody, phox2a antibody, phox2a.S antibody
- 背景
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PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
Protein Interaction Partner: SP1, PHOX2A, HAND2, PRKACA, ATF6B, CREBBP, JUN,
Protein Size: 284 - 分子量
- 30 kDa
- 基因ID
- 401
- NCBI登录号
- NM_005169, NP_005160
- UniProt
- O14813
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