SNF8 抗体 (N-Term)
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- 抗原 See all SNF8 抗体
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNF8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- MHRRGVGAGA IAKKKLAEAK YKERGTVLAE DQLAQMSKQL DMFKTNLEEF
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against SNF8. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EAP30
- Top Product
- Discover our top product SNF8 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 258 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
- 别名
- EAP30 (SNF8 产品)
- 别名
- d11moh34 antibody, vps22 antibody, Dot3 antibody, EAP30 antibody, VPS22 antibody, D11moh34 antibody, RGD1310144 antibody, D11Moh34 antibody, D11MOH34 antibody, zgc:101578 antibody, SNF8, ESCRT-II complex subunit antibody, eap30 subunit of ell complex, putative antibody, EAP30 subunit of ELL complex antibody, SNF8, ESCRT-II complex subunit S homeolog antibody, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) antibody, snf8 antibody, TA17290 antibody, TVAG_107410 antibody, Bm1_05145 antibody, SNF8 antibody, Snf8 antibody, snf8.S antibody
- 背景
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ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL, MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741], Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM].
Alias Symbols: Dot3, EAP30, VPS22
Protein Interaction Partner: GOLGA2, VPS25, TRIM54, VAC14, UBC, BCAT1, SUV39H2, ACBD3, DUS3L, WDR12, PRMT6, RPUSD2, KDM1A, EFTUD2, TTC1, HARS, GTF2F1, GTF2E1, ELL, RBP1, MCM2, ADORA1, METTL14, NUDCD3, RILP, VPS36, CHMP6, VPS28, SNF8, TSG101, VPS20, NIF3L1, DVL2,
Protein Size: 258 - 分子量
- 29 kDa
- 基因ID
- 11267
- NCBI登录号
- NM_007241, NP_009172
- UniProt
- Q96H20
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