RIPK3 抗体 (N-Term)
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- 抗原 See all RIPK3 抗体
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, Pig, 马, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RIPK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- GGSQSGTGSG EPGGTLGYLA PELFVNVNRK ASTASDVYSF GILMWAVLAG
- 预测反应
- Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 91%
- 产品特性
- This is a rabbit polyclonal antibody against RIPK3. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RIPK3
- Top Product
- Discover our top product RIPK3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 518 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
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Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
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- 抗原
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
- 别名
- RIPK3 (RIPK3 产品)
- 别名
- RIPK3 antibody, RIP3 antibody, 2610528K09Rik antibody, AW107945 antibody, Rip3 antibody, Hcyp2 antibody, receptor interacting serine/threonine kinase 3 antibody, receptor interacting serine/threonine kinase 3 S homeolog antibody, receptor-interacting serine-threonine kinase 3 antibody, RIPK3 antibody, ripk3.S antibody, Ripk3 antibody
- 背景
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RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Alias Symbols: RIP3, RIP3 beta, RIP3 gamma
Protein Interaction Partner: BMH1, RFX6, FADD, RIPK1, CASP8, INPP5K, CDC37, STIP1, PYGL, FKBP5, FKBP4, CTNND1, UBC, XIAP, BIRC3, BIRC2, TICAM1, TRAF2, TNFRSF1A,
Protein Size: 518 - 分子量
- 57 kDa
- 基因ID
- 11035
- NCBI登录号
- NM_006871, NP_006862
- UniProt
- Q9Y572
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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