HDAC6 抗体 (N-Term)
-
- 抗原 See all HDAC6 抗体
- HDAC6 (Histone Deacetylase 6 (HDAC6))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Pig, Cow
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This HDAC6 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
- 序列
- VGLQGMDLNL EAEALAGTGL VLDEQLNEFH CLWDDSFPEG PERLHAIKEQ
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against HDAC6. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC6
- Top Product
- Discover our top product HDAC6 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 1215 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- HDAC6 (Histone Deacetylase 6 (HDAC6))
- 别名
- HDAC6 (HDAC6 产品)
- 背景
-
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Alias Symbols: HD6, JM21
Protein Interaction Partner: HSP90B1, ACTB, UBC, TRIM50, MYH10, DYNC1H1, DDIT3, ELAVL1, MAPK3, MAPK1, RUNX2, TUBA1B, SUMO1, RANBP9, NEDD8, ADRB2, ATXN3, MEF2B, SQSTM1, HSP90AA1, RASSF2, SLMAP, SAV1, CTTNBP2NL, BAG3, SETD8, TUBB, HSPA8, HSPA6, HSPA5, HSPA4, HSPA2, HSPA1L, DNAJA1, ETV6
Protein Size: 1215 - 分子量
- 131 kDa, 17 kDa
- 基因ID
- 10013
- NCBI登录号
- NM_006044
- UniProt
- Q9UBN7
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
-