MXI1 抗体 (Middle Region)
-
- 抗原 See all MXI1 抗体
- MXI1 (MAX Interactor 1 (MXI1))
-
抗原表位
- Middle Region
-
适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Saccharomyces cerevisiae
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MXI1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- LNKAKAHIKK LEEAERKSQH QLENLEREQR FLKWRLEQLQ GPQEMERIRM
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 75%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against MXI1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MXI1
- Top Product
- Discover our top product MXI1 Primary Antibody
-
anti-MAX Interactor 1 (MXI1) (AA 1-182) antibody
MXI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-MAX Interactor 1 (MXI1) antibodyMXI1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 73-182) antibodyMXI1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-MAX Interactor 1 (MXI1) (N-Term) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 75-173) antibodyMXI1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) antibodyMXI1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 215-264) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Pig, Bat, Hamster, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (N-Term) antibodyMXI1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 176-225) antibodyMXI1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Pig, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAX Interactor 1 (MXI1) (AA 76-295) antibodyMXI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 295 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- MXI1 (MAX Interactor 1 (MXI1))
- 别名
- MXI1 (MXI1 产品)
- 别名
- mxi antibody, mad2 antibody, mxd2 antibody, xmxi1 antibody, MGC89544 antibody, MXI1 antibody, etID309773.22 antibody, fb16b12 antibody, fb55f03 antibody, wu:fb16b12 antibody, wu:fb55f03 antibody, wu:fd06a08 antibody, wu:fz74f10 antibody, ENSMUSG00000067085 antibody, Gm10197 antibody, Mad2 antibody, bHLHc11 antibody, MXI-WR antibody, MAD2 antibody, MXD2 antibody, MXI antibody, MAX interactor 1, dimerization protein antibody, max interactor 1, dimerization protein antibody, MAX interactor 1, dimerization protein L homeolog antibody, mxi1 antibody, MXI1 antibody, Mxi1 antibody, mxi1.L antibody
- 背景
-
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The MXI1 gene encodes a transcriptional repressor protein thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in MXI1 are frequently found in patients with prostate tumors.Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Alias Symbols: MAD2, MGC43220, MXD2, MXI, bHLHc11
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-9, KRTAP10-7, KRT40, RPL23AP32, CALCOCO2, MAX, ENTPD5, UBC, APP, CDC20, BUB1B, SIN3B, SIN3A, SMC3, MYC,
Protein Size: 295 - 分子量
- 26 kDa
- 基因ID
- 4601
- NCBI登录号
- NM_130439, NP_569157
- UniProt
- P50539
- 途径
- Maintenance of Protein Location
-
