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PAX2A 抗体 (Middle Region)

PAX2A 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 兔, 绵羊, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777232
发货至: 中国
  • 抗原 See all PAX2A 抗体
    PAX2A (Paired Box Gene 2a (PAX2A))
    抗原表位
    • 8
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 76
    • 36
    • 24
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 兔, 绵羊, 豚鼠, 马
    宿主
    • 73
    • 7
    克隆类型
    • 67
    • 13
    多克隆
    标记
    • 38
    • 8
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This PAX2A antibody is un-conjugated
    应用范围
    • 52
    • 46
    • 16
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    DPVGSYSING ILGIPRSNGE KRKRDEDVSE GSVPNGDSQS GVDSLRKHLR
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against PAX2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of Human PAX2
    Top Product
    Discover our top product PAX2A Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 393 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Palmieri, Gojis, Rudraraju, Stamp-Vincent, Wilson, Langdon, Gourley, Faratian: "Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance." in: British journal of cancer, Vol. 108, Issue 10, pp. 2039-44, (2013) (PubMed).

    Viringipurampeer, Ferreira, DeMaria, Yoon, Shan, Moosajee, Gregory-Evans, Ngai, Gregory-Evans: "Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development." in: Human molecular genetics, Vol. 21, Issue 10, pp. 2357-69, (2012) (PubMed).

    Lee, Doberstein, Baumgarten, Wieland, Ungerer, Bürger, Hardt, Boehncke, Pfeilschifter, Mihic-Probst, Mittelbronn, Gutwein: "PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells." in: PLoS ONE, Vol. 6, Issue 8, pp. e22312, (2011) (PubMed).

    Yu, Moriniere, Birke, Neumann, Fuchshofer, Kampik, Bloemendal, Welge-Lussen: "Reactivation of optic nerve head astrocytes by TGF-beta2 and H2O2 is accompanied by increased Hsp32 and Hsp47 expression." in: Investigative ophthalmology & visual science, Vol. 50, Issue 4, pp. 1707-17, (2009) (PubMed).

    Hurtado, Holmes, Geistlinger, Hutcheson, Nicholson, Brown, Jiang, Howat, Ali, Carroll: "Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen." in: Nature, Vol. 456, Issue 7222, pp. 663-6, (2008) (PubMed).

    Yu, Fuchshofer, Birke, Priglinger, Eibl, Kampik, Bloemendal, Welge-Lussen: "Hypoxia/reoxygenation and TGF-beta increase alphaB-crystallin expression in human optic nerve head astrocytes." in: Experimental eye research, Vol. 84, Issue 4, pp. 694-706, (2007) (PubMed).

  • 抗原
    PAX2A (Paired Box Gene 2a (PAX2A))
    别名
    PAX2 (PAX2A 产品)
    别名
    PAPRS antibody, Opdc antibody, Pax-2 antibody, Pax-2a antibody, XPax-2 antibody, XPax2 antibody, pax-2 antibody, pax2 antibody, xPax-2a antibody, PAXZF-B antibody, cb378 antibody, noi antibody, pax-b antibody, pax2.1 antibody, pax2a1 antibody, pax[zf-b] antibody, paxb antibody, pax2.2 antibody, paired box 2 antibody, paired box 2 L homeolog antibody, paired box 2a antibody, paired box 2b antibody, PAX2 antibody, Pax2 antibody, pax2.L antibody, pax2a antibody, pax2b antibody
    背景
    PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.
    Alias Symbols: -
    Protein Interaction Partner: BBS7, BBS4, BBS2, BBS1, RB1, BRCA1, SFRP2, PAXIP1, WT1, MAPK8IP1, MAPK8, ID2,
    Protein Size: 393
    分子量
    42 kDa
    基因ID
    5076
    NCBI登录号
    NM_000278, NP_000269
    UniProt
    Q02962
    途径
    Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation
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