PAX2A 抗体 (Middle Region)
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- 抗原 See all PAX2A 抗体
- PAX2A (Paired Box Gene 2a (PAX2A))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 兔, 绵羊, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAX2A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- DPVGSYSING ILGIPRSNGE KRKRDEDVSE GSVPNGDSQS GVDSLRKHLR
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PAX2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human PAX2
- Top Product
- Discover our top product PAX2A Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 393 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance." in: British journal of cancer, Vol. 108, Issue 10, pp. 2039-44, (2013) (PubMed).
: "Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development." in: Human molecular genetics, Vol. 21, Issue 10, pp. 2357-69, (2012) (PubMed).
: "PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells." in: PLoS ONE, Vol. 6, Issue 8, pp. e22312, (2011) (PubMed).
: "Reactivation of optic nerve head astrocytes by TGF-beta2 and H2O2 is accompanied by increased Hsp32 and Hsp47 expression." in: Investigative ophthalmology & visual science, Vol. 50, Issue 4, pp. 1707-17, (2009) (PubMed).
: "Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen." in: Nature, Vol. 456, Issue 7222, pp. 663-6, (2008) (PubMed).
: "Hypoxia/reoxygenation and TGF-beta increase alphaB-crystallin expression in human optic nerve head astrocytes." in: Experimental eye research, Vol. 84, Issue 4, pp. 694-706, (2007) (PubMed).
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Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance." in: British journal of cancer, Vol. 108, Issue 10, pp. 2039-44, (2013) (PubMed).
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- 抗原
- PAX2A (Paired Box Gene 2a (PAX2A))
- 别名
- PAX2 (PAX2A 产品)
- 别名
- PAPRS antibody, Opdc antibody, Pax-2 antibody, Pax-2a antibody, XPax-2 antibody, XPax2 antibody, pax-2 antibody, pax2 antibody, xPax-2a antibody, PAXZF-B antibody, cb378 antibody, noi antibody, pax-b antibody, pax2.1 antibody, pax2a1 antibody, pax[zf-b] antibody, paxb antibody, pax2.2 antibody, paired box 2 antibody, paired box 2 L homeolog antibody, paired box 2a antibody, paired box 2b antibody, PAX2 antibody, Pax2 antibody, pax2.L antibody, pax2a antibody, pax2b antibody
- 背景
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PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.
Alias Symbols: -
Protein Interaction Partner: BBS7, BBS4, BBS2, BBS1, RB1, BRCA1, SFRP2, PAXIP1, WT1, MAPK8IP1, MAPK8, ID2,
Protein Size: 393 - 分子量
- 42 kDa
- 基因ID
- 5076
- NCBI登录号
- NM_000278, NP_000269
- UniProt
- Q02962
- 途径
- Carbohydrate Homeostasis, Stem Cell Maintenance, Tube Formation
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