Aurora A 抗体 (C-Term)
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- 抗原 See all Aurora A (AURKA) 抗体
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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抗原表位
- C-Term
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适用
- 人, Cow, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aurora A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ARDLISRLLK HNPSQRPMLR EVLEHPWITA NSSKPSNCQN KESASKQS
- 预测反应
- Cow: 80%, Human: 100%, Sheep: 80%
- 产品特性
- This is a rabbit polyclonal antibody against AURKA. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human AURKA
- Top Product
- Discover our top product AURKA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 403 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Aurora A (AURKA) (Aurora Kinase A (AURKA))
- 别名
- AURKA (AURKA 产品)
- 背景
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AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Alias Symbols: AIK, ARK1, AURA, AURORA2, BTAK, MGC34538, STK15, STK6, STK7, PPP1R47
Protein Interaction Partner: CHFR, GADD45A, RPLP2, RPLP0, RPL38, RPL30, RPL27, RPL22, RPL12, RPL11, PSMB7, PSMB5, PSMA6, PSMA5, PSMA1, MAPK6, PPP6C, PCMT1, YBX1, NPM1, NCL, MFAP4, LYZ, ILF3, ILF2, IARS, HSPD1, HSP90AB1, HSP90AA1, HSPA9, HSPA8, HSPA5, HSPA2, HSPA1A, HNRNPU, HNRNPA2B1,
Protein Size: 403 - 分子量
- 46 kDa
- 基因ID
- 6790
- NCBI登录号
- NM_003600, NP_003591
- UniProt
- O14965
- 途径
- Cell Division Cycle, Asymmetric Protein Localization
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