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- 抗原 See all DAB2 抗体
- DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DAB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EVETSATNGQ PDQQAAPKAP SKKEKKKGPE KTDEYLLARF KGDGVKYKAK
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against DAB2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human DAB2
- Top Product
- Discover our top product DAB2 Primary Antibody
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anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 1-770) antibody
DAB2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 31-130) antibodyDAB2 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 743-770), (C-Term) antibodyDAB2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23472 unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (pSer24) antibodyDAB2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 673-770) antibodyDAB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C8 unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 1-770) antibodyDAB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D6 unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (C-Term) antibodyDAB2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 743-770) antibodyDAB2 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) (AA 624-650), (C-Term) antibodyDAB2 适用: 小鼠 WB 宿主: 兔 Polyclonal RB40861 unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))
- 别名
- DAB2 (DAB2 产品)
- 别名
- DOC-2 antibody, DOC2 antibody, 5730435J12Rik antibody, AA960054 antibody, AI957090 antibody, D15Wsu122e antibody, D630005B22Rik antibody, Doc-2 antibody, Doc2 antibody, p96 antibody, DAB2, clathrin adaptor protein antibody, disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) antibody, Dab, mitogen-responsive phosphoprotein, homolog 2 antibody, disabled 2, mitogen-responsive phosphoprotein antibody, DAB2 antibody, dab2 antibody, Dab2 antibody
- 背景
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This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: Fcho2, CPSF7, SMURF2, YLPM1, C14orf166, ACOT9, CPSF6, SF3B2, MALT1, HSPH1, SEC23B, SEC24B, NUP155, CDC16, TRIO, TFAP2A, AURKA, PYCR1, PRDX1, MYO6, HSPA1B, HNRNPL, GRB2, FN1, CLTC, AP2M1, CFTR, CCNT1, ACTB, AHCY, AP2B1, AP2A2, AP2A1, DYT10, ATXN1L, SH3KBP1
Protein Size: 552 - 分子量
- 60 kDa
- 基因ID
- 1601
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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