CES1 抗体 (N-Term)
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- 抗原 See all CES1 抗体
- CES1 (Carboxylesterase 1 (CES1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CES1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VLGKFVSLEG FAQPVAIFLG IPFAKPPLGP LRFTPPQPAE PWSFVKNATS
- 预测反应
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 86%, Yeast: 83%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against CES1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CES1
- Top Product
- Discover our top product CES1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 567 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CES1 (Carboxylesterase 1 (CES1))
- 别名
- CES1 (CES1 产品)
- 背景
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CES1 is one of the enzymes responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia.Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene.Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: ACAT, CEH, CES2, HMSE, HMSE1, MGC117365, PCE-1, SES1, TGH, REH
Protein Interaction Partner: BMPR2, GUSB, CES1,
Protein Size: 567 - 分子量
- 61 kDa
- 基因ID
- 1066
- NCBI登录号
- NM_001025194, NP_001020365
- UniProt
- P23141
- 途径
- Monocarboxylic Acid Catabolic Process
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