GSTM1 抗体 (N-Term)
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- 抗原 See all GSTM1 抗体
- GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 山羊, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GSTM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILCYI
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
- 产品特性
- This is a rabbit polyclonal antibody against GSTM1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GSTM1
- Top Product
- Discover our top product GSTM1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 218 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Seasonal heat stress affects adipose tissue proteome toward enrichment of the Nrf2-mediated oxidative stress response in late-pregnant dairy cows." in: Journal of proteomics, Vol. 158, pp. 52-61, (2017) (PubMed).
: "MicroRNA regulation in Ames dwarf mouse liver may contribute to delayed aging." in: Aging cell, Vol. 9, Issue 1, pp. 1-18, (2010) (PubMed).
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Seasonal heat stress affects adipose tissue proteome toward enrichment of the Nrf2-mediated oxidative stress response in late-pregnant dairy cows." in: Journal of proteomics, Vol. 158, pp. 52-61, (2017) (PubMed).
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- 抗原
- GSTM1 (Glutathione S-Transferase mu 1 (GSTM1))
- 别名
- GSTM1 (GSTM1 产品)
- 别名
- GST1 antibody, GSTM1-1 antibody, GSTM1a-1a antibody, GSTM1b-1b antibody, GTH4 antibody, GTM1 antibody, H-B antibody, MU antibody, MU-1 antibody, GSTA3 antibody, Gstb-1 antibody, Gstb1 antibody, gst-mu antibody, gst1 antibody, gstm1 antibody, gstm2 antibody, gth4 antibody, gtm1 antibody, glutathione S-transferase mu 1 antibody, glutathione S-transferase M1 antibody, glutathione S-transferase, mu 1 antibody, glutathione S-transferase Mu 1 antibody, glutathione S-transferase mu 2 (muscle) antibody, glutathione S-transferase mu 1 L homeolog antibody, GSTM1 antibody, Gstm1 antibody, LOC100356307 antibody, GSTM2 antibody, LOC100731426 antibody, gstm1.L antibody
- 背景
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Cytosolic and membrane-bound forms of glutathione S-transferase are two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM1 a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
Alias Symbols: GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MGC26563, MU, MU-1
Protein Interaction Partner: GSTM3, UBC, IQCB1, MAP3K5, GSTM2, GSTM1,
Protein Size: 218 - 分子量
- 26 kDa
- 基因ID
- 2944
- NCBI登录号
- NM_000561, NP_000552
- UniProt
- P46439
- 途径
- Negative Regulation of Transporter Activity
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