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PKLR 抗体 (N-Term)

PKLR 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776945
发货至: 中国
  • 抗原 See all PKLR 抗体
    PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
    抗原表位
    • 14
    • 9
    • 9
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 69
    • 29
    • 19
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, Pig, 斑马鱼
    宿主
    • 66
    • 10
    克隆类型
    • 68
    • 8
    多克隆
    标记
    • 35
    • 8
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PKLR antibody is un-conjugated
    应用范围
    • 50
    • 39
    • 36
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    STSIIATIGP ASRSVERLKE MIKAGMNIAR LNFSHGSHEY HAESIANVRE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against PKLR. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PKLR
    Top Product
    Discover our top product PKLR Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 543 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
    别名
    PKLR (PKLR 产品)
    别名
    PK1 antibody, PKL antibody, PKR antibody, PKRL antibody, RPK antibody, Pklg antibody, wu:fd15e01 antibody, wu:fi37e08 antibody, pk1 antibody, PKLR antibody, Pk-1 antibody, Pk1 antibody, R-PK antibody, pklr antibody, pyruvate kinase L/R antibody, pyruvate kinase, liver and RBC antibody, pyruvate kinase, liver and RBC L homeolog antibody, pyruvate kinase liver and red blood cell antibody, pyruvate kinase PKLR-like antibody, PKLR antibody, Pklr antibody, pklr antibody, pklr.L antibody, LOC100621940 antibody
    背景
    PKLR is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).The protein encoded by this gene is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Alternatively spliced transcript variants encoding distinct isoforms have been described.
    Alias Symbols: PK1, PKL, RPK, PKR, PKRL
    Protein Interaction Partner: UBC, WWOX, SUMO4, CLEC4G, PCNA, OTUD5, USPL1, USP3, MYOC, KIF23, ARHGEF6, PXN, PAK1,
    Protein Size: 543
    分子量
    58 kDa
    基因ID
    5313
    NCBI登录号
    NM_181871, NP_870986
    途径
    Ribonucleoside Biosynthetic Process
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