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ASL 抗体 (Middle Region)

Name: ASL 抗体 (Middle Region)
SKU: ABIN2776928
Availability: OutOfStock

ASL 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, 犬, 山羊, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-ASL Antibody Titration: 5. (ASL 抗体 (Middle Region))

Lanes: Lane1: 10 ug COS-7 cell lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:2000 Gene Name: ASL Submitted by: Shawn Elms. (ASL 抗体 (Middle Region))

2 images

(2 references)

产品编号 ABIN2776928

发货至: 中国

Datasheet as PDF

抗原 See all ASL 抗体

ASL (Argininosuccinate Lyase (ASL))
抗原表位
15

11

5

2

1

1

1

1

1

1

1

1

1

1
Middle Region
适用
58

14

10

5

5

5

5

5

4

3

3

3

3

3

3

2

2
人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, 犬, 山羊, Saccharomyces cerevisiae
宿主
53

5
兔
Compatible Secondaries
克隆类型
55

3
多克隆
标记
29

4

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ASL antibody is un-conjugated
应用范围
39

13

13

11

11

11

7

6

4

3

2

2

1

1

1
Western Blotting (WB)

序列

LILYCTKEFS FVQLSDAYST GSSLMPQKKN PDSLELIRSK AGRVFGREDK

预测反应

Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against ASL. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human ASL

Top Product

Discover our top product ASL Primary Antibody
anti-Argininosuccinate Lyase (ASL) antibody
ASL 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 1-300) antibody
ASL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 2-300) antibody
ASL 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) antibody
ASL 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 1-464) antibody
ASL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) antibody
ASL 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 1-464) antibody
ASL 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 260-309) antibody
ASL 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (AA 101-150) antibody
ASL 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated

anti-Argininosuccinate Lyase (ASL) (Middle Region) antibody
ASL 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 444 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Tanaka, Nagao, Mori, Tsutsumi: "A novel stop codon mutation (X465Y) in the argininosuccinate lyase gene in a patient with argininosuccinic aciduria." in: The Tohoku journal of experimental medicine, Vol. 198, Issue 2, pp. 119-24, (2003) (PubMed).
抗原

ASL (Argininosuccinate Lyase (ASL))

别名

ASL (ASL 产品)

别名

ASAL antibody, 2510006M18Rik antibody, zgc:63532 antibody, BA4879 antibody, PSPTO0125 antibody, Adl antibody, Asl antibody, argininosuccinate lyase antibody, argininosuccinate lyase ArgH antibody, adenylosuccinate lyase antibody, argininosuccinate lyase L homeolog antibody, ASL antibody, Asl antibody, asl antibody, argH2 antibody, argH antibody, arg7 antibody, CNC04420 antibody, STHERM_c13370 antibody, Adsl antibody, asl.L antibody, ARG7 antibody

背景

ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: ASAL
Protein Interaction Partner: WDYHV1, ASL, GINS4, NCDN, TUFM, PDHA1, NEDD8, HK1, GDI1, BAG3, OVGP1, HMOX1, FBP1, CSNK2A2, UBC, QARS,
Protein Size: 444

分子量

49 kDa

基因ID

435

NCBI登录号

NM_001024944, NP_001020115

UniProt

P04424

途径

Response to Growth Hormone Stimulus