PDZK1 抗体 (N-Term)
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- 抗原 See all PDZK1 抗体
- PDZK1 (PDZ Domain Containing 1 (PDZK1))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 马, 犬, 豚鼠, 兔, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDZK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- NSVTLLVLDG DSYEKAVKTR VDLKELGQSQ KEQGLSDNIL SPVMNGGVQT
- 预测反应
- Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PDZK1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PDZK1
- Top Product
- Discover our top product PDZK1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 519 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PDZK1 (PDZ Domain Containing 1 (PDZK1))
- 别名
- PDZK1 (PDZK1 产品)
- 别名
- xpdzk1 antibody, PDZK1 antibody, CAP70 antibody, CLAMP antibody, NHERF-3 antibody, NHERF3 antibody, PDZD1 antibody, 1700023D20Rik antibody, 2610507N21Rik antibody, 4921513F16Rik antibody, AI267131 antibody, AI314638 antibody, AL022680 antibody, D3Ertd537e antibody, Pdzd1 antibody, mPDZK1 antibody, Clamp antibody, PDZ domain containing 1 antibody, PDZ domain containing 1 L homeolog antibody, PDZK1 antibody, pdzk1.L antibody, pdzk1 antibody, Pdzk1 antibody
- 背景
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PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. It may be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, it may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. PDZK1 may play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. PDZK1 may potentiate the CFTR chloride channel activity. It may function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. PDZK1 may be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.
Alias Symbols: CAP70, CLAMP, NHERF3, PDZD1, NHERF-3
Protein Interaction Partner: AKT1, CDC37, Ptgir, ABCC4, CFTR, APP, Klhl17, Syngap1, Dlg4, SLC26A6, SLC22A4, SLCO1A2, SLC15A2, PDZK1IP1, SLC22A11, SLC22A12, AKAP10, SLC22A5, ABCC2, SCARB1, CLCN3, PEX5, ABCA1, SSTR5, SLC17A1, SLC9A3, GFAP, SLC34A3, FARP2, SLK, SLC9A3R1, SLC9A3R2, UBE2I
Protein Size: 519 - 分子量
- 57 kDa
- 基因ID
- 5174
- NCBI登录号
- NM_002614, NP_002605
- UniProt
- Q5T2W1
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