UGT1A6 抗体 (C-Term)
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- 抗原 See all UGT1A6 抗体
- UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 斑马鱼, 马, 绵羊, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UGT1A6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- APHLRPAAHD LTWYQYHSLD VIGFLLAVVL TVAFITFKCC AYGYRKCLGK
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against UGT1A6. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human UGT1A6
- Top Product
- Discover our top product UGT1A6 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 532 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))
- 别名
- UGT1A6 (UGT1A6 产品)
- 别名
- GNT1 antibody, HLUGP antibody, HLUGP1 antibody, UDPGT antibody, UDPGT 1-6 antibody, UGT1 antibody, UGT1A6S antibody, UGT1F antibody, UGT1A10 antibody, UGT1A6 antibody, UGT1A7 antibody, UGT1A8 antibody, UGT1A9 antibody, DKFZP469F071 antibody, UGT1A5 antibody, UGT antibody, Udpgt antibody, Ugt1 antibody, Ugt1a7 antibody, UGT1-06 antibody, UGT1.6 antibody, Ugt1a6b antibody, Ugt1a6 antibody, UDP glucuronosyltransferase family 1 member A6 antibody, UDP glucuronosyltransferase family 1 member A1 antibody, UDP glucuronosyltransferase 1 family, polypeptide A6 antibody, UDP-glucuronosyltransferase 1-1 antibody, UDP glucuronosyltransferase 1 family, polypeptide A6 S homeolog antibody, UDP-glucuronosyltransferase 1-6 antibody, UGT1A6 antibody, UGT1A1 antibody, LOC739942 antibody, ugt1a6.S antibody, ugt1a6 antibody, LOC100481084 antibody, Ugt1a6 antibody, UGT1-6 antibody, LOC100731122 antibody
- 背景
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UGT1A6 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.
Alias Symbols: GNT1, HLUGP, HLUGP1, MGC29860, UDPGT, UGT1, UGT1F, UGT1A6S, UDPGT 1-6
Protein Size: 532 - 分子量
- 58 kDa
- 基因ID
- 54578
- NCBI登录号
- NM_001072, NP_001063
- UniProt
- P19224
- 途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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