Renin 抗体 (C-Term)
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- 抗原 See all Renin (REN) 抗体
- Renin (REN)
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠, 犬, 绵羊, Cow, 豚鼠, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Renin antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- YSSKKLCTLA IHAMDIPPPT GPTWALGATF IRKFYTEFDR RNNRIGFALA
- 预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against REN. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human REN
- Top Product
- Discover our top product REN Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 406 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Angiotensin-II promotes Na+ uptake in larval zebrafish, Danio rerio, in acidic and ion-poor water." in: The Journal of endocrinology, Vol. 220, Issue 3, pp. 195-205, (2014) (PubMed).
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Angiotensin-II promotes Na+ uptake in larval zebrafish, Danio rerio, in acidic and ion-poor water." in: The Journal of endocrinology, Vol. 220, Issue 3, pp. 195-205, (2014) (PubMed).
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- 抗原
- Renin (REN)
- 别名
- REN (REN 产品)
- 背景
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Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Mutations in this gene have been shown to cause familial hyperproreninemia.Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.
Alias Symbols: FLJ10761, HNFJ2
Protein Interaction Partner: AGT, ATP6AP2, KCTD15, PCSK5, RENBP, PCSK1, M6PR, CTSB,
Protein Size: 406 - 分子量
- 45 kDa
- 基因ID
- 5972
- NCBI登录号
- NM_000537, NP_000528
- UniProt
- P00797
- 途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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