MAT1A 抗体 (C-Term)
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- 抗原 See all MAT1A 抗体
- MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 斑马鱼, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAT1A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VAKSLVKAGL CRRVLVQVSY AIGVAEPLSI SIFTYGTSQK TERELLDVVH
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against MAT1A. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human MAT1A
- Top Product
- Discover our top product MAT1A Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 395 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
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Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
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- 抗原
- MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
- 别名
- MAT1A (MAT1A 产品)
- 别名
- MAT antibody, MATA1 antibody, SAMS antibody, SAMS1 antibody, AdoMet antibody, SADE antibody, SAS antibody, AI046368 antibody, Ams antibody, wu:fi35e01 antibody, zgc:55442 antibody, methionine adenosyltransferase 1A antibody, methionine adenosyltransferase I, alpha antibody, MAT1A antibody, Mat1a antibody, mat1a antibody
- 背景
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MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. MAT1A is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in its gene are associated with methionine adenosyltransferase deficiency.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
Alias Symbols: MAT, MATA1, SAMS, SAMS1
Protein Interaction Partner: MAT1A, UBC, IST1, MVK, MAT2A,
Protein Size: 395 - 分子量
- 44 kDa
- 基因ID
- 4143
- NCBI登录号
- NM_000429, NP_000420
- UniProt
- Q00266
- 途径
- Mitotic G1-G1/S Phases, M Phase, Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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