FZD8 抗体 (N-Term)
(2 references)-
- 抗原 See all FZD8 抗体
- FZD8 (Frizzled Family Receptor 8 (FZD8))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FZD8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PDTLCMDYNR TDLTTAAPSP PRRLPPPPPG EQPPSGSGHG RPPGARPPHR
- 预测反应
- Dog: 100%, Human: 100%, Mouse: 93%, Rat: 92%
- 产品特性
- This is a rabbit polyclonal antibody against FZD8. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FZD8
- Top Product
- Discover our top product FZD8 Primary Antibody
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anti-Frizzled Family Receptor 8 (FZD8) (AA 55-233) antibody
FZD8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) antibodyFZD8 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (AA 72-161) antibodyFZD8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (Extracellular Domain) antibodyFZD8 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠, Cow, 猴, 非洲爪蟾, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyVerified FZD8 适用: 人 WB, ELISA, IHC, IF, IEM 宿主: 山羊 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (C-Term) antibodyFZD8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 8 (FZD8) (N-Term) antibodyFZD8 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 694 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "MicroRNA-375 suppresses human colorectal cancer metastasis by targeting Frizzled 8." in: Oncotarget, Vol. 7, Issue 26, pp. 40644-40656, (2016) (PubMed).
: "Tumor-initiating cells and FZD8 play a major role in drug resistance in triple-negative breast cancer." in: Molecular cancer therapeutics, Vol. 12, Issue 4, pp. 491-8, (2013) (PubMed).
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: "MicroRNA-375 suppresses human colorectal cancer metastasis by targeting Frizzled 8." in: Oncotarget, Vol. 7, Issue 26, pp. 40644-40656, (2016) (PubMed).
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- 抗原
- FZD8 (Frizzled Family Receptor 8 (FZD8))
- 别名
- FZD8 (FZD8 产品)
- 背景
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FZD8 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Alias Symbols: FZ-8, hFZ8
Protein Interaction Partner: WNT1, LRP5, LRP6, SUMO1, GOPC, RYK,
Protein Size: 694 - 分子量
- 73 kDa
- 基因ID
- 8325
- NCBI登录号
- NM_031866, NP_114072
- UniProt
- Q9H461
- 途径
- WNT signaling
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