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ERI1 抗体 (N-Term)

Name: ERI1 抗体 (N-Term)
SKU: ABIN2776656
Availability: OutOfStock

ERI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-THEX1 Antibody Titration: 0. (ERI1 抗体 (N-Term))

Host: Rabbit Target Name: ERI1 Sample Tissue: Human Lung Tumor lysates Antibody Dilution: 1ug/ml (ERI1 抗体 (N-Term))

2 images

(1 reference)

产品编号 ABIN2776656

发货至: 中国

Datasheet as PDF

抗原 See all ERI1 抗体

ERI1 (Exoribonuclease 1 (ERI1))
抗原表位
15

8

8

7

6

3

2

1

1

1

1

1

1

1
N-Term
适用
44

34

20

5

3

2

2

2

2

1
人
宿主
58

2
兔
Compatible Secondaries
克隆类型
58

2
多克隆
标记
25

5

5

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ERI1 antibody is un-conjugated
应用范围
34

27

13

13

7

4

4

3

3

1

1
Western Blotting (WB)

序列

SKFITSSASD FSDPVYKEIA ITNGCINRMS KEELRAKLSE FKLETRGVKD

预测反应

Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 100%, Rat: 79%

产品特性

This is a rabbit polyclonal antibody against THEX1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human ERI1

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anti-Exoribonuclease 1 (ERI1) antibody
ERI1 适用: 人, 大鼠, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated

anti-Exoribonuclease 1 (ERI1) (AA 2-66) antibody
ERI1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Exoribonuclease 1 (ERI1) (AA 1-345) antibody
ERI1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Exoribonuclease 1 (ERI1) (AA 51-150) antibody
ERI1 适用: 小鼠 ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Exoribonuclease 1 (ERI1) (C-Term) antibody
ERI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Exoribonuclease 1 (ERI1) (AA 231-280) antibody
ERI1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Exoribonuclease 1 (ERI1) (AA 29-78) antibody
ERI1 适用: 人, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated

anti-Exoribonuclease 1 (ERI1) (C-Term) antibody
ERI1 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated

anti-Exoribonuclease 1 (ERI1) (AA 2-249) antibody
ERI1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Exoribonuclease 1 (ERI1) antibody
ERI1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 349 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Kupsco, Wu, Marzluff, Thapar, Duronio: "Genetic and biochemical characterization of Drosophila Snipper: A promiscuous member of the metazoan 3'hExo/ERI-1 family of 3' to 5' exonucleases." in: RNA (New York, N.Y.), Vol. 12, Issue 12, pp. 2103-17, (2006) (PubMed).
抗原

ERI1 (Exoribonuclease 1 (ERI1))

别名

THEX1 (ERI1 产品)

别名

THEX1 antibody, thex1 antibody, zgc:110635 antibody, hexo antibody, Eri-1 antibody, 3'HEXO antibody, HEXO antibody, 3'hexo antibody, 3110010F15Rik antibody, Thex1 antibody, eri-1 antibody, RGD1308378 antibody, exoribonuclease 1 antibody, three prime repair exonuclease 1 antibody, exoribonuclease 1 L homeolog antibody, 3'-5' exonuclease eri-1 antibody, ERI1 antibody, CpipJ_CPIJ003945 antibody, eri1 antibody, eri1.L antibody, Eri1 antibody, eri-1 antibody

背景

RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Alias Symbols: HEXO, THEX1, 3'HEXO
Protein Interaction Partner: UBC, HNRNPD, HHV8GK18_gp81, SLBP,
Protein Size: 38

分子量

349 kDa

基因ID

90459

NCBI登录号

NM_153332, NP_699163

UniProt

Q8IV48