A1CF 抗体 (N-Term)
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- 抗原 See all A1CF 抗体
- A1CF (APOBEC1 Complementation Factor (A1CF))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This A1CF antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EAVCLGTCPE PEASMSTAIP GLKKGNNALQ SIILQTLLEK ENGQRKYGGP
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against A1CF. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human A1CF
- Top Product
- Discover our top product A1CF Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 594 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- A1CF (APOBEC1 Complementation Factor (A1CF))
- 别名
- A1CF (A1CF 产品)
- 别名
- ACF antibody, ACF64 antibody, ACF65 antibody, APOBEC1CF antibody, ASP antibody, 1810073H04Rik antibody, Acf antibody, A1cft antibody, Apobec-1 antibody, acf antibody, acf64 antibody, acf65 antibody, apobec1cf antibody, asp antibody, A1CF antibody, APOBEC1 complementation factor antibody, apobec1 complementation factor antibody, APOBEC1 complementation factor L homeolog antibody, A1CF antibody, A1cf antibody, a1cf antibody, a1cf.L antibody
- 背景
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Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.
Alias Symbols: ACF, ACF64, ACF65, APOBEC1CF, ASP, MGC163391, RP11-564C4.2
Protein Interaction Partner: SDPR, TRAF1, REL, FHL3, KHSRP, SYNCRIP, TNPO2, CELF2, APOBEC1,
Protein Size: 594 - 分子量
- 65 kDa
- 基因ID
- 29974
- NCBI登录号
- NM_138933, NP_620311
- UniProt
- Q9NQ94
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