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- 抗原 See all EXOSC6 抗体
- EXOSC6 (Exosome Component 6 (EXOSC6))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, Pig, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EXOSC6 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LYAADEEEAP GTRDPTRLRP VYARAGLLSQ AKGSAYLEAG GTKVLCAVSG
- 预测反应
- Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against EXOSC6. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC6
- Top Product
- Discover our top product EXOSC6 Primary Antibody
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anti-Exosome Component 6 (EXOSC6) (N-Term) antibody
EXOSC6 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 小鼠, 大鼠, Cow, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 6 (EXOSC6) (N-Term) antibodyEXOSC6 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 272 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- EXOSC6 (Exosome Component 6 (EXOSC6))
- 别名
- EXOSC6 (EXOSC6 产品)
- 别名
- exosc6 antibody, RAR-gamma antibody, id:ibd1130 antibody, wu:fe17d05 antibody, zgc:110071 antibody, EAP4 antibody, MTR3 antibody, Mtr3p antibody, hMtr3p antibody, p11 antibody, 2610510N21Rik antibody, C76919 antibody, Mtr3 antibody, exosome component 6 antibody, EXOSC6 antibody, exosc6 antibody, CpipJ_CPIJ018071 antibody, Exosc6 antibody
- 背景
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EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.
Alias Symbols: p11, EAP4, MTR3, Mtr3p, hMtr3p
Protein Interaction Partner: CEP250, DCP1B, EXOSC6, CHPF, MIF4GD, XRN1, NDUFA13, MRPL4, EXOSC1, MRPS18B, UPF2, RAB3GAP2, SKIV2L2, GSE1, EXOSC7, EXOSC8, ZFP36, TUFM, EXOSC10, MAN2C1, ESRRA, C1QBP, AICDA, DIS3L, EXOSC4, EXOSC3, CUL3, ELAVL1, HDGF, UBC, EXOSC5, DNAJC30, MOCS3, MPP6, EXO
Protein Size: 272 - 分子量
- 30 kDa
- 基因ID
- 118460
- NCBI登录号
- NM_058219, NP_478126
- UniProt
- Q5RKV6
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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