DGCR8 抗体 (N-Term)
(3 references)-
- 抗原 See all DGCR8 抗体
- DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DGCR8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- DKKDEENELD QEKRVEYAVL DELEDFTDNL ELDEEGAGGF TAKAIVQRDR
- 预测反应
- Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 77%
- 产品特性
- This is a rabbit polyclonal antibody against DGCR8. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DGCR8
- Top Product
- Discover our top product DGCR8 Primary Antibody
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anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 1-773) antibody
DGCR8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 1-773) antibodyDGCR8 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 675-771) antibodyDGCR8 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G3 unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 675-771) antibodyDGCR8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 1-773) antibodyDGCR8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (C-Term) antibodyDGCR8 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 180-229) antibodyDGCR8 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (AA 439-466) antibodyDGCR8 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) antibodyDGCR8 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 2H2 unconjugated Recombinant Antibody
anti-DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (pSer377) antibodyDGCR8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 773 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "DGCR8 is essential for tumor progression following PTEN loss in the prostate." in: EMBO reports, Vol. 16, Issue 9, pp. 1219-32, (2015) (PubMed).
: "Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery." in: PLoS ONE, Vol. 7, Issue 7, pp. e40662, (2012) (PubMed).
: "NMDA mediated contextual conditioning changes miRNA expression." in: PLoS ONE, Vol. 6, Issue 9, pp. e24682, (2011) (PubMed).
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: "DGCR8 is essential for tumor progression following PTEN loss in the prostate." in: EMBO reports, Vol. 16, Issue 9, pp. 1219-32, (2015) (PubMed).
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- 抗原
- DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
- 别名
- DGCR8 (DGCR8 产品)
- 别名
- MGC78846 antibody, DGCR8 antibody, gy1 antibody, dgcrk6 antibody, C22orf12 antibody, DGCRK6 antibody, Gy1 antibody, pasha antibody, D16H22S1742E antibody, D16H22S788E antibody, D16Wis2 antibody, N41 antibody, Vo59c07 antibody, si:ch211-106a19.4 antibody, wu:fc23f08 antibody, wu:fc38f06 antibody, DGCR8 microprocessor complex subunit L homeolog antibody, DiGeorge syndrome critical region gene 8 antibody, DGCR8 microprocessor complex subunit antibody, DGCR8, microprocessor complex subunit antibody, microRNA 3618 antibody, dgcr8.L antibody, DGCR8 antibody, dgcr8 antibody, Dgcr8 antibody, MIR3618 antibody
- 背景
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DGCR8 contains 2 DRBM (double-stranded RNA-binding) domains and 1 WW domain. It may play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies.
Alias Symbols: C22orf12, DGCRK6, Gy1, pasha
Protein Interaction Partner: MEOX2, PYCRL, DROSHA, RAE1, MAPK1, PRMT1, ERH, CDKN2A, BMI1, SRPK2, SRPK1, CDT1, NAT10, PLEK2, RPRD2, MAPRE2, PRPF4, FLII, APP, CUL3, DDX17, HNRNPR, NCL, ILF3, HSPA8, HSPA5, HNRNPU, HNRNPH1, FUS, DHX9, DDX5,
Protein Size: 773 - 分子量
- 85 kDa
- 基因ID
- 54487
- NCBI登录号
- NM_022720, NP_073557
- UniProt
- Q8WYQ5
- 途径
- Regulatory RNA Pathways
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