KCNN3 抗体 (C-Term)
-
- 抗原 See all KCNN3 抗体
- KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
-
抗原表位
- C-Term
-
适用
- 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 兔, 马
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This KCNN3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ITELNDRSED LEKQIGSLES KLEHLTASFN SLPLLIADTL RQQQQQLLSA
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against KCNN3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human KCNN3
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 736 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
- 别名
- KCNN3 (KCNN3 产品)
- 别名
- KCa2.3 antibody, SK3 antibody, SKCA3 antibody, hSK3 antibody, potassium calcium-activated channel subfamily N member 3 antibody, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 antibody, Kcnn3 antibody, KCNN3 antibody
- 背景
-
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
Alias Symbols: SK3, hSK3, SKCA3, KCa2.3
Protein Interaction Partner: UBC, RAB5A, DNM2, CAV1, APP, CALM1,
Protein Size: 736 - 分子量
- 81 kDa
- 基因ID
- 3782
- NCBI登录号
- NM_002249, NP_002240
- UniProt
- Q9UGI6
-