KCNK3 抗体 (C-Term)
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- 抗原 See all KCNK3 抗体
- KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))
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抗原表位
- C-Term
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适用
- 大鼠, 人, 小鼠, 犬, 绵羊, Cow, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- TCVEQSHSSP GGGGRYSDTP SRRCLCSGAP RSAISSVSTG LHSLSTFRGL
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against KCNK3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human KCNK3
- Top Product
- Discover our top product KCNK3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 394 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Functional role of TASK-1 in the heart: studies in TASK-1-deficient mice show prolonged cardiac repolarization and reduced heart rate variability." in: Basic research in cardiology, Vol. 106, Issue 1, pp. 75-87, (2010) (PubMed).
: "The role of TASK1 in aldosterone production and its expression in normal adrenal and aldosterone-producing adenomas." in: Clinical endocrinology, Vol. 73, Issue 1, pp. 22-9, (2010) (PubMed).
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Functional role of TASK-1 in the heart: studies in TASK-1-deficient mice show prolonged cardiac repolarization and reduced heart rate variability." in: Basic research in cardiology, Vol. 106, Issue 1, pp. 75-87, (2010) (PubMed).
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- 抗原
- KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))
- 别名
- KCNK3 (KCNK3 产品)
- 别名
- si:dkey-164m15.1 antibody, K2p3.1 antibody, OAT1 antibody, PPH4 antibody, TASK antibody, TASK-1 antibody, TBAK1 antibody, cTBAK-1 antibody, Task-1 antibody, rTASK antibody, KCNK3 antibody, potassium channel, subfamily K, member 3a antibody, potassium two pore domain channel subfamily K member 3 antibody, potassium channel, subfamily K, member 3 antibody, kcnk3a antibody, KCNK3 antibody, Kcnk3 antibody
- 背景
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KCNK3 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The gene product is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
Alias Symbols: TASK, TBAK1, K2p3.1, TASK-1
Protein Interaction Partner: YWHAB, COPB1, YWHAG, YWHAE, SFN, YWHAZ, YWHAQ, S100A10, YWHAH,
Protein Size: 394 - 分子量
- 43 kDa
- 基因ID
- 3777
- NCBI登录号
- NM_002246, NP_002237
- UniProt
- O14649
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