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RFX6 抗体 (Middle Region)

This anti-RFX6 antibody is a 兔 多克隆 antibody detecting RFX6 in WB. Suitable for 人, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 大鼠 和 斑马鱼.
产品编号 ABIN2776023
发货至: 中国

Quick Overview for RFX6 抗体 (Middle Region) (ABIN2776023)

抗原

See all RFX6 抗体
RFX6 (Regulatory Factor X 6 (RFX6))

适用

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人, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 大鼠, 斑马鱼

宿主

  • 17
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克隆类型

  • 19
多克隆

标记

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This RFX6 antibody is un-conjugated

应用范围

  • 5
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Western Blotting (WB)
  • 抗原表位

    • 5
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    • 1
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    Middle Region

    序列

    LGTRGHSKYH YYGIGIKESS AYYHSVYSGK GLTRFSGSKL KNEGGFTRKY

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against Rfx6. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of MOUSE Rfx6
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RFX6 (Regulatory Factor X 6 (RFX6))

    别名

    Rfx6

    背景

    Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin. Not required for pancreatic PP (polypeptide-producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes.
    Protein Size: 524

    分子量

    57 kDa

    基因ID

    320995

    途径

    Carbohydrate Homeostasis
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