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CREM 抗体 (C-Term)

CREM 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776017
发货至: 中国
  • 抗原 See all CREM 抗体
    CREM (CAMP Responsive Element Modulator (CREM))
    抗原表位
    • 16
    • 15
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 47
    • 39
    • 23
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊, 斑马鱼
    宿主
    • 59
    • 3
    • 1
    克隆类型
    • 61
    • 1
    多克隆
    标记
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CREM antibody is un-conjugated
    应用范围
    • 36
    • 26
    • 26
    • 21
    • 18
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against Crem. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Crem
    Top Product
    Discover our top product CREM Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 357 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CREM (CAMP Responsive Element Modulator (CREM))
    别名
    Crem (CREM 产品)
    别名
    CREM antibody, ICER antibody, CREM-2 antibody, hCREM-2 antibody, ICERI antibody, Icer antibody, cAMP responsive element modulator antibody, CREM antibody, Crem antibody
    背景
    Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.
    Alias Symbols: Icer
    Protein Interaction Partner: Stub1, Ubc,
    Protein Size: 357
    分子量
    39 kDa
    基因ID
    25620
    NCBI登录号
    NM_001110860, NP_001104330
    UniProt
    Q03061
    途径
    Retinoic Acid Receptor Signaling Pathway
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