CREM 抗体 (C-Term)
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- 抗原 See all CREM 抗体
- CREM (CAMP Responsive Element Modulator (CREM))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CREM antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Crem. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Crem
- Top Product
- Discover our top product CREM Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 357 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- CREM (CAMP Responsive Element Modulator (CREM))
- 别名
- Crem (CREM 产品)
- 别名
- CREM antibody, ICER antibody, CREM-2 antibody, hCREM-2 antibody, ICERI antibody, Icer antibody, cAMP responsive element modulator antibody, CREM antibody, Crem antibody
- 背景
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Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.
Alias Symbols: Icer
Protein Interaction Partner: Stub1, Ubc,
Protein Size: 357 - 分子量
- 39 kDa
- 基因ID
- 25620
- NCBI登录号
- NM_001110860, NP_001104330
- UniProt
- Q03061
- 途径
- Retinoic Acid Receptor Signaling Pathway
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