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KEAP1 抗体 (C-Term)

Name: KEAP1 抗体 (C-Term)
SKU: ABIN2775979
Availability: OutOfStock

KEAP1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-KEAP1 Antibody Titration: 1. (KEAP1 抗体 (C-Term))

IHC

Host: Rabbit Target Name: KEAP1 Sample Type: HepG2 Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1. (KEAP1 抗体 (C-Term))

4 images

(1 reference)

产品编号 ABIN2775979

发货至: 中国

Datasheet as PDF

抗原 See all KEAP1 抗体

KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
抗原表位
15

15

14

11

10

6

3

2

2

1

1

1

1

1

1

1

1

1
C-Term
适用
88

59

35

22

17

6

5

4

3

3

3

3

2

1
人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼
宿主
85

8

1
兔
Compatible Secondaries
克隆类型
85

9
多克隆
标记
42

8

6

6

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This KEAP1 antibody is un-conjugated
应用范围
77

40

31

26

26

15

9

7

6

4

4

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

TWTFVAPMKH RRSALGITVH QGRIYVLGGY DGHTFLDSVE CYDPDTDTWS

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against KEAP1. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human KEAP1

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anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibody
KEAP1 适用: 人, 小鼠 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1B4 unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibody
KEAP1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7G4B10 unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibody
KEAP1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F10B6 unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibody
KEAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 65-160) antibody
KEAP1 适用: 人, 小鼠, 大鼠, Pig, 兔 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-286) antibody
KEAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 41-53) antibody
Verified KEAP1 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-624) antibody
KEAP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 327-624) antibody
KEAP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (N-Term) antibody
KEAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 624 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Konishi, Baumgarten, Ishida, Saitoh, Anker, Springer: "Protein levels in Keap1-Nrf2 system in human failing heart." in: International journal of cardiology, Vol. 225, pp. 62-64, (2016) (PubMed).
抗原

KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

别名

KEAP1 (KEAP1 产品)

别名

INrf2 antibody, KLHL19 antibody, INRF2 antibody, mKIAA0132 antibody, Inrf2 antibody, fb36f11 antibody, keap1 antibody, wu:fb36f11 antibody, KEAP1 antibody, klhl19 antibody, zgc:171654 antibody, kelch like ECH associated protein 1 antibody, kelch-like ECH-associated protein 1 antibody, Kelch-like ECH-associated protein 1 antibody, kelch-like ECH-associated protein 1a antibody, kelch like ECH associated protein 1 L homeolog antibody, kelch-like ECH-associated protein 1b antibody, KEAP1 antibody, Keap1 antibody, keap1a antibody, keap1 antibody, keap1.L antibody, keap1b antibody

背景

KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Alias Symbols: INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454
Protein Interaction Partner: OXR1, ZSCAN32, LSM3, KLHL3, FBXW11, MAPKBP1, NUDT4, DPP3, RBX1, ATG5, SQSTM1, PTMA, PRKAG1, NFE2L2, MAD2L1, GYPA, ETF1, BCL2, CUL3, RECK, UBC, PGAM5, FAM117B, WDR83, CCNB1IP1, HSP90AA1, XPO1, MCMBP, KEAP1, SLK, MCM3, IKBKB, AMER1, GPRASP2, PRKCE, NFE2L1,
Protein Size: 624

分子量

70 kDa

基因ID

9817

NCBI登录号

NM_203500, NP_987096

UniProt

Q14145

途径

Maintenance of Protein Location