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CBX3 抗体 (Middle Region)

CBX3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775975
发货至: 中国
  • 抗原 See all CBX3 抗体
    CBX3 (Chromobox Homolog 3 (CBX3))
    抗原表位
    • 24
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 108
    • 70
    • 54
    • 11
    • 9
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔
    宿主
    • 83
    • 25
    • 2
    克隆类型
    • 77
    • 33
    多克隆
    标记
    • 50
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CBX3 antibody is un-conjugated
    应用范围
    • 51
    • 28
    • 28
    • 28
    • 27
    • 18
    • 18
    • 14
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    WEPEENLDCP ELIEAFLNSQ KAGKEKDGTK RKSLSDSESD DSKSKKKRDA
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against CBX3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CBX3
    Top Product
    Discover our top product CBX3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 183 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CBX3 (Chromobox Homolog 3 (CBX3))
    别名
    CBX3 (CBX3 产品)
    别名
    HECH antibody, HP1-GAMMA antibody, HP1Hs-gamma antibody, Hp1-gamma antibody, HP1g antibody, M32 antibody, cbx3 antibody, cbx3a antibody, xhp1g antibody, wu:fb61b02 antibody, zgc:153397 antibody, chromobox 3 antibody, chromobox 3 L homeolog antibody, chromobox protein homolog 3 pseudogene antibody, chromobox homolog 3a (HP1 gamma homolog, Drosophila) antibody, CBX3 antibody, Cbx3 antibody, cbx3.L antibody, LOC100355282 antibody, cbx3a antibody
    背景
    At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. CBX3 binds DNA and is a component of heterochromatin. CBX3 also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of CBX3 may explain the association of heterochromatin with the inner nuclear membrane.At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
    Alias Symbols: HECH, HP1-GAMMA, HP1Hs-gamma
    Protein Interaction Partner: UBC, SUMO1, MDM2, EED, SUZ12, RNF2, WDR1, DCK, ADSS, THOP1, TALDO1, PTMS, OXCT1, IDH1, HSPE1, HECW2, PARK2, VHL, CHAF1A, AURKB, AURKA, EHMT2, FN1, TRIM39, HNF1A, CBX5, MDC1, TP53BP1, YWHAE, TNKS1BP1, H2AFY, ATXN7L2, CACNB4, BAHD1, CUL1, PCGF6, SIRT7, RYBP
    Protein Size: 183
    分子量
    21 kDa
    基因ID
    11335
    NCBI登录号
    NM_007276, NP_009207
    UniProt
    Q13185
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