CBX1 抗体 (N-Term)
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- 抗原 See all CBX1 抗体
- CBX1 (Chromobox Homolog 1 (CBX1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Pig, Cow, 兔, 马, Saccharomyces cerevisiae, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN
- 预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
- 产品特性
- This is a rabbit polyclonal antibody against CBX1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CBX1
- Top Product
- Discover our top product CBX1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 185 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response." in: Nature, Vol. 453, Issue 7195, pp. 682-6, (2008) (PubMed).
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HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response." in: Nature, Vol. 453, Issue 7195, pp. 682-6, (2008) (PubMed).
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- 抗原
- CBX1 (Chromobox Homolog 1 (CBX1))
- 别名
- CBX1 (CBX1 产品)
- 别名
- CBX antibody, HP1-BETA antibody, HP1Hs-beta antibody, HP1Hsbeta antibody, M31 antibody, MOD1 antibody, p25beta antibody, Cbx antibody, Cbx-rs2 antibody, E430007M08Rik antibody, HP1B antibody, Hp1beta antibody, cbx1 antibody, wu:fe14b09 antibody, zgc:55739 antibody, zgc:86924 antibody, chromobox 1 antibody, chromobox homolog 1a (HP1 beta homolog Drosophila) antibody, chromobox 1 S homeolog antibody, chromobox homolog 1b (HP1 beta homolog Drosophila) antibody, CBX1 antibody, Cbx1 antibody, cbx1a antibody, cbx1.S antibody, cbx1b antibody
- 背景
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CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the in
Alias Symbols: CBX, HP1-BETA, HP1Hs-beta, M31, MOD1, p25beta, HP1Hsbeta
Protein Interaction Partner: PRDM6, SUMO1, UBC, RNF2, PARK2, NR2F6, VHL, EHMT2, ABI3BP, VTN, TRIM39, CBX5, HIST1H3B, KLF11, HIST3H3, PCNA, MECP2, ADNP, POGZ, ADNP2, CBX3, TRIM28, CHAF1A, HIST1H4F, XRCC6, CHD4, H2AFB1, NSL1, SUMO2, HIST1H3A, Mad2l2, Cbx1, DNMT3B, ZNF382, H3F3A, SUV420
Protein Size: 185 - 分子量
- 21 kDa
- 基因ID
- 10951
- NCBI登录号
- NM_006807, NP_006798
- UniProt
- P83916
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