ZYX 抗体 (Middle Region)
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- 抗原 See all ZYX 抗体
- ZYX (Zyxin (ZYX))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, Cow, 马, 犬, 豚鼠, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZYX antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE
- 预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 79%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against ZYX. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ZYX
- Top Product
- Discover our top product ZYX Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 572 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ZYX (Zyxin (ZYX))
- 别名
- ZYX (ZYX 产品)
- 别名
- BcDNA:LD06023 antibody, CG32018 antibody, DLim-1 antibody, DmLIM-1 antibody, Dmel\\CG32018 antibody, Lim102EF antibody, ZYX102 antibody, Zyx102 antibody, Zyx102EF antibody, lim antibody, zyx102 antibody, zyxin antibody, zgc:171680 antibody, ZYX antibody, zyx antibody, MGC145270 antibody, ESP-2 antibody, HED-2 antibody, 9530098H06Rik antibody, R75157 antibody, Zyxin antibody, zyxin antibody, zyxin S homeolog antibody, zyx-1 antibody, Zyx antibody, zyx antibody, ZYX antibody, EDI_201420 antibody, zyx.S antibody
- 背景
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TRIM50 is an E3 ubiquitin-protein ligase.Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
Alias Symbols: ESP-2, HED-2
Protein Interaction Partner: RTN4IP1, YPEL3, IMP3, PHF21A, PDLIM5, LIN7A, SUMO1, NEDD8, FAM129B, CORO1B, CAND1, PUF60, PAPOLA, NUDC, SEC23B, SEC24C, HIST1H4A, UGP2, TARS, PXN, GART, GARS, APEH, FN1, HIPK3, VCAM1, UBC, UBL7, UFC1, UBXN7, ZC3H7B, TTLL12, FERMT2, TOMM34, AHCYL1, SSSCA1,
Protein Size: 572 - 分子量
- 61 kDa
- 基因ID
- 7791
- NCBI登录号
- NM_003461, NP_003452
- UniProt
- Q15942
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