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ZYX 抗体 (Middle Region)

ZYX 适用: 人, 大鼠, Cow, 马, 犬, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775767
发货至: 中国
  • 抗原 See all ZYX 抗体
    ZYX (Zyxin (ZYX))
    抗原表位
    • 8
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 64
    • 23
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, Cow, 马, 犬, 豚鼠, 兔
    宿主
    • 53
    • 10
    • 1
    克隆类型
    • 48
    • 15
    多克隆
    标记
    • 29
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    This ZYX antibody is un-conjugated
    应用范围
    • 35
    • 15
    • 12
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE
    预测反应
    Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Rabbit: 79%, Rat: 86%
    产品特性
    This is a rabbit polyclonal antibody against ZYX. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human ZYX
    Top Product
    Discover our top product ZYX Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 572 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ZYX (Zyxin (ZYX))
    别名
    ZYX (ZYX 产品)
    别名
    BcDNA:LD06023 antibody, CG32018 antibody, DLim-1 antibody, DmLIM-1 antibody, Dmel\\CG32018 antibody, Lim102EF antibody, ZYX102 antibody, Zyx102 antibody, Zyx102EF antibody, lim antibody, zyx102 antibody, zyxin antibody, zgc:171680 antibody, ZYX antibody, zyx antibody, MGC145270 antibody, ESP-2 antibody, HED-2 antibody, 9530098H06Rik antibody, R75157 antibody, Zyxin antibody, zyxin antibody, zyxin S homeolog antibody, zyx-1 antibody, Zyx antibody, zyx antibody, ZYX antibody, EDI_201420 antibody, zyx.S antibody
    背景
    TRIM50 is an E3 ubiquitin-protein ligase.Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
    Alias Symbols: ESP-2, HED-2
    Protein Interaction Partner: RTN4IP1, YPEL3, IMP3, PHF21A, PDLIM5, LIN7A, SUMO1, NEDD8, FAM129B, CORO1B, CAND1, PUF60, PAPOLA, NUDC, SEC23B, SEC24C, HIST1H4A, UGP2, TARS, PXN, GART, GARS, APEH, FN1, HIPK3, VCAM1, UBC, UBL7, UFC1, UBXN7, ZC3H7B, TTLL12, FERMT2, TOMM34, AHCYL1, SSSCA1,
    Protein Size: 572
    分子量
    61 kDa
    基因ID
    7791
    NCBI登录号
    NM_003461, NP_003452
    UniProt
    Q15942
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