FHL1 抗体 (C-Term)
(12 references)-
- 抗原 See all FHL1 抗体
- FHL1 (Four and A Half LIM Domains 1 (FHL1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 绵羊, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FHL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- YYCVDCYKNF VAKKCAGCKN PITGFGKGSS VVAYEGQSWH DYCFHCKKCS
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
- 产品特性
- This is a rabbit polyclonal antibody against FHL1. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human FHL1
- Top Product
- Discover our top product FHL1 Primary Antibody
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anti-Four and A Half LIM Domains 1 (FHL1) (AA 23-120) antibody
FHL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A9 unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) antibodyFHL1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (Internal Region) antibodyVerified FHL1 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) antibodyFHL1 适用: 人, 大鼠, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) antibodyFHL1 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (AA 51-100) antibodyFHL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 绵羊, Pig, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (AA 214-240), (C-Term) antibodyFHL1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19645 unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (N-Term) antibodyFHL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 绵羊, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (AA 13-240) antibodyFHL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (AA 1-280) antibodyFHL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 280 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology." in: Neuromuscular disorders : NMD, Vol. 27, Issue 4, pp. 338-351, (2017) (PubMed).
: "Exome Sequencing Identified a Splice Site Mutation in FHL1 that Causes Uruguay Syndrome, an X-Linked Disorder With Skeletal Muscle Hypertrophy and Premature Cardiac Death." in: Circulation. Cardiovascular genetics, Vol. 9, Issue 2, pp. 130-5, (2016) (PubMed).
: "Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits." in: Biochemical and biophysical research communications, Vol. 450, Issue 1, pp. 353-9, (2014) (PubMed).
: "A case of adult-onset reducing body myopathy presenting a novel clinical feature, asymmetrical involvement of the sternocleidomastoid and trapezius muscles." in: Journal of the neurological sciences, Vol. 343, Issue 1-2, pp. 206-10, (2014) (PubMed).
: "High prevalence of epigenetic inactivation of the human four and a half LIM domains 1 gene in human oral cancer." in: International journal of oncology, Vol. 42, Issue 1, pp. 141-50, (2012) (PubMed).
: "Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis." in: Molecular bioSystems, Vol. 7, Issue 4, pp. 1185-96, (2011) (PubMed).
: "Four and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K(v1.5)." in: PLoS ONE, Vol. 6, Issue 10, pp. e26524, (2011) (PubMed).
: "Consequences of mutations within the C terminus of the FHL1 gene." in: Neurology, Vol. 73, Issue 7, pp. 543-51, (2009) (PubMed).
: "Mutations of the FHL1 gene cause Emery-Dreifuss muscular dystrophy." in: American journal of human genetics, Vol. 85, Issue 3, pp. 338-53, (2009) (PubMed).
: "An X-linked myopathy with postural muscle atrophy and generalized hypertrophy, termed XMPMA, is caused by mutations in FHL1." in: American journal of human genetics, Vol. 82, Issue 1, pp. 88-99, (2008) (PubMed).
: "X-linked dominant scapuloperoneal myopathy is due to a mutation in the gene encoding four-and-a-half-LIM protein 1." in: American journal of human genetics, Vol. 82, Issue 1, pp. 208-13, (2008) (PubMed).
: "Skeletal muscle LIM protein 1 (SLIM1/FHL1) induces alpha 5 beta 1-integrin-dependent myocyte elongation." in: American journal of physiology. Cell physiology, Vol. 285, Issue 6, pp. C1513-26, (2003) (PubMed).
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: "Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology." in: Neuromuscular disorders : NMD, Vol. 27, Issue 4, pp. 338-351, (2017) (PubMed).
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- 抗原
- FHL1 (Four and A Half LIM Domains 1 (FHL1))
- 别名
- FHL1 (FHL1 产品)
- 别名
- fhl1 antibody, MGC89165 antibody, FHL1 antibody, DKFZp468O1927 antibody, fhl antibody, fhla antibody, zgc:92025 antibody, FHL-1 antibody, FHL1A antibody, FHL1B antibody, FLH1A antibody, KYOT antibody, SLIM antibody, SLIM-1 antibody, SLIM1 antibody, SLIMMER antibody, XMPMA antibody, KyoT antibody, Fhl1 antibody, four and a half LIM domains 1 antibody, four and a half LIM domains 1a antibody, Four and a half LIM domains protein 1 antibody, four and a half LIM domains 1 S homeolog antibody, fhl1 antibody, FHL1 antibody, fhl1a antibody, fhl1.S antibody, Fhl1 antibody
- 背景
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LIM proteins, named for 'LIN11, ISL1, and MEC3,' are defined by the possession of a highly conserved double zinc finger motif called the LIM domain. FHL1 may play an important role during the early stages of skeletal muscle differentiation, specifically in alpha5beta1-integrin-mediated signaling pathways.
Alias Symbols: KYOT, SLIM, FHL-1, FHL1A, FHL1B, FLH1A, SLIM1, XMPMA, SLIM-1, SLIMMER
Protein Interaction Partner: SUMO2, UBC, SRPK1, SMAD4, SMAD3, SMAD2, LMNA, CSNK1D, NRIP1, ESR1, HIVEP3, SMURF1, UBE2E2, STAT4, RING1, RBPJ, FHL1, KCNA5, PRNP, USP15, HHV8GK18_gp81, SP1, TXNIP, DEAF1, PDE4DIP, AKAP12, EED, HES1, DBN1, CBX4, FHL2, SRF, MYBPC1,
Protein Size: 280 - 分子量
- 32 kDa
- 基因ID
- 2273
- NCBI登录号
- NM_001449, NP_001440
- UniProt
- Q6IB30
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